grant
Women’s Health and Aging: Developmental Pathways Underlying Life Course Risk
Organization UNIVERSITY OF WASHINGTONLocation SEATTLE, UNITED STATESPosted 1 Feb 2026Deadline 30 Nov 2030
NIHUS FederalResearch GrantFY20260-11 years old21+ years oldActive Follow-upAddressAdultAdult HumanAdult-Onset Diabetes MellitusAgeAgingArchivesAssayBMIBMI percentileBMI z-scoreBioassayBiologicalBiological AgingBiological AssayBirthBloodBlood PressureBlood Reticuloendothelial SystemBlood SampleBlood specimenBody WeightBody mass indexCardiometabolic DiseaseCardiometabolic DisorderCardiovascular DiseasesChildChild CareChild RearingChild YouthChildren (0-21)D-GlucoseDataData CollectionDevelopmentDextroseDisadvantagedDiseaseDisorderEating DisordersEmotionalEthnic OriginEthnicityExposure toFamilyFemaleFemale HealthFundingGlucoseGoalsHealthHealth behaviorHumulin RInsulinInsulin ResistanceInterventionIntervention StrategiesInterviewKetosis-Resistant Diabetes MellitusKnowledgeLife CycleLife Cycle StagesLife ExperienceLinkLiteratureMaturity-Onset Diabetes MellitusMediatingMediatorMental DepressionMental HealthMental HygieneMetabolic syndromeModelingMuellerian inhibiting hormoneMullerian-inhibiting factorNICHDNIDDMNational Institute of Child Health and Human DevelopmentNational Institutes of HealthNon-Insulin Dependent DiabetesNon-Insulin-Dependent Diabetes MellitusNoninsulin Dependent DiabetesNoninsulin Dependent Diabetes MellitusNovolin RObesityOutcomeOvarian agingParentingParenting behaviorParticipantParturitionPathway interactionsPhysiologicPhysiologicalPrepuberal statePsychological HealthPubertyPuericultureQuetelet indexRaceRacesRegular InsulinResearchRiskRisk FactorsRoleSeriesSlow-Onset Diabetes MellitusSocio-economic statusSocioeconomic StatusStable Diabetes MellitusStagingStrategic PlanningT2 DMT2DT2DMTestingTimeTransmissionType 2 Diabetes MellitusType 2 diabetesType II Diabetes MellitusType II diabetesUnited States National Institutes of HealthVisitWeight GainWeight IncreaseWomanWomen's HealthWorkaccelerated agingaccelerated biological ageaccelerated biological agingaccelerated epigenetic ageaccelerated epigenetic agingaccelerated pace of epigenetic agingacceleration in epigenetic ageactive followupadiposityadult onset diabetesadulthoodage accelerationagesaging biological markeraging biomarkeraging human ovaryaging induced epigenetic changeaging markeraging ovaryaging processaging-associated epigenetic changeaging-related epigenetic changeanti-mullerian factoranti-mullerian hormonebiologicbiological process of agebody weight gainbody weight increasecardiometaboliccardiometabolic riskcardiometabolismcardiovascular disorderchildrearingcohortcorpulencedepressiondevelopmentaldisabilityearly life exposureepigenetic agingepigenetic mechanisms in agingepigenetic modifications in agingepigenetic regulation of agingexperienceexperiences among menfaster epigenetic agingfaster rates of epigenetic agingfollow upfollow-upfollowed upfollowupgirlshealth related behaviorhealthspanhealthy life spanimprovedincreased epigenetic ageincreased epigenetic agingincreased rates of epigenetic aginginsulin resistantinsulin toleranceketosis resistant diabeteskidslife coursemale experiencematurity onset diabetesmenmen's experiencemid lifemid-lifemiddle agemiddle agedmidlifemortalitymullerian inhibiting substancemullerian regression factormullerian-inhibiting hormonemullerian-inhibitory substancemultimorbiditymultiple chronic conditionsobesity riskovarian senescenceovulatory senescencepandemicpandemic diseasepathwayphysical conditioningphysical healthprepubertalprepubertypreventpreventingprospectiveprotective factorspubertal timingracialracial backgroundracial originrapid epigenetic agingrecruitreproductive agingreproductive cell senescencereproductive senescenceresponserisk for obesityrisk of obesitysocialsocial rolesocio-economic positionsocioeconomic positionstandard measuresubstance usesubstance usingtransmission processtype 2 DMtype II DMtype two diabeteswt gainyoungster♀
Description preview
PROJECT SUMMARY
The current application is responsive to the NIH-Wide Strategic Plan for Research on the Health of Women
(2024-2028) led by the Office of Research on Women’s Health. It addresses Strategic Goal 1 (Research) under
Objective 6 to advance women’s health through the study of key transition periods. Here, we focus on female
pubertal…
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