grant
Whole Body Effects of PAE Across the Life Span: Early Markers of & Clinical Interventions for Children and Adolescents in Ukraine
Organization UNIVERSITY OF CALIFORNIA, SAN DIEGOLocation LA JOLLA, UNITED STATESPosted 12 Aug 2022Deadline 30 Apr 2027
NIHUS FederalResearch GrantFY20260-11 years old10 year old10 years of age14 year old14 years of age21+ years old3-D Images3-D image3D image3D images4 year old4 years of ageASCVDAddressAdolescentAdolescent YouthAdultAdult HumanAffectAgeAlcohol Chemical ClassAlcoholsAnxietyAssayAtherosclerosisAtherosclerotic Cardiovascular DiseaseAutoimmune DiseasesBioassayBiological AssayBirthBlood SampleBlood capillariesBlood specimenBurn injuryBurnsCardiovascular DiseasesCardiovascular ManifestationCare GiversCaregiversCategoriesCharacteristicsChildChild YouthChildhoodChildren (0-21)Chronic DiseaseChronic IllnessClinicalClinical DataClinical EvaluationClinical TestingClinical TreatmentCognitive DisturbanceCognitive ImpairmentCognitive declineCognitive function abnormalCohort StudiesCollaborationsCommunitiesComplexCore FacilityDataDiabetes MellitusDiagnosisDiagnosticDiagnostic FindingsDiet HabitsDietary HabitsDietary intakeDiseaseDisorderDisturbance in cognitionEating BehaviorEvaluation ResearchFASDFamilyFe deficiencyFetal Alcohol ExposureFetal Alcohol Spectrum DisorderFetal Alcohol SyndromeFetal ETOH ExposureFetal Ethanol ExposureFetal alcohol effectsFutureGeneralized GrowthGoalsGrowthGuidelinesHealth Care CostsHealth CostsHealth systemHearingHyperlipemiaHyperlipidemiaHypertensionImpaired cognitionIn Utero Alcohol ExposureIn Utero ETOH ExposureIn Utero Ethanol ExposureIndividualInflammationInsulin ResistanceInterventionInvestigatorsKnowledgeLaboratoriesLengthLifeLife CycleLife Cycle StagesLong-term cohort studyLongitudinal cohort studyMeasurementMeasuresMediatingMental DepressionMetabolicMicroRNAsMyocardial depressionMyocardial dysfunctionNail plateNailsOutcomeParticipantParturitionPatternPhysical activityPremature AgingPremature aging syndromePrenatal Alcohol ExposurePrenatal ETOH ExposurePrenatal Ethanol ExposurePrevalencePreventionProbabilityRecommendationResearchResearch PersonnelResearch ResourcesResearchersResourcesSample SizeSamplingSightSigns and SymptomsSleepSleep disturbancesStructureTelemedicineTelomere ShorteningThree-Dimensional ImageTissue GrowthTranslatingUkraineVascular Hypertensive DiseaseVascular Hypertensive DisorderVisionWorkaberrant sleepadulthoodadverse childhood eventsadverse childhood experiencesage 10age 10 yearsage 14age 14 yearsage 4age 4 yearsage groupagesalcohol-exposed pregnancyalcoholic embryopathyatheromatosisatherosclerotic diseaseatherosclerotic vascular diseaseautoimmune conditionautoimmune disorderautoimmunity diseaseburnedcapillarycapillary bedcardiac dysfunctioncardiovascular disorderchild health carechronic disorderclinical interventionclinical testclinical therapyco-morbidco-morbid depressionco-morbid with depressionco-morbidityco-morbidity with depressioncognitive dysfunctioncognitive losscohortcohort research studycohort surveycomorbid depressioncomorbid with depressioncomorbiditycomorbidity with depressioncopingdepressiondepression co-morbiditydepression comorbiditydevelopmental diseasedevelopmental disorderdiabetesdisease classificationdisorder classificationdisrupted sleepdisturbed sleepeating habitembryofetal alcohol syndromeembryopathia alcoholicaevaluation investigationexposed to alcohol prenatallyfetal diagnosisfour year oldfour years of agefourteen year oldfourteen years of agegestation ETOH exposuregestation alcohol exposuregestation ethanol exposuregestational ethanol exposureheart dysfunctionhigh blood pressurehyperpiesiahyperpiesishypertensive diseasehypertensive disorderimpaired glucose toleranceimpaired sleepimprovedinflammation markerinflammatory markerinsulin resistantinsulin toleranceinvestigate evaluationiron deficiencyirregular sleepjuvenilejuvenile humankidslife courselife spanlifespanmiRNAnosologyontogenypediatricpediatric carepediatric health carepre-clinicalpreclinicalpregnancy ETOH exposurepregnancy alcohol exposurepregnancy ethanol exposureprenatalprenatal alcohol effectprenatally alcohol exposedprenatally exposed to alcoholpreventpreventingrecruitremediationresearch clinical testingsleep disruptionsleep dysregulationsleep/wake disruptionsleep/wake disturbancestudy evaluationsurvey evaluationtelomeretelomere attritionten year oldten years of agetrial regimentrial treatmentunbornvisual functionyoungster
Description preview
Project Summary
Numerous comorbidities have been identified as relatively common among children and adolescents with
prenatal alcohol exposure (PAE) or fetal alcohol spectrum disorders (FASDs) including sleep disturbances,
hypertension, abnormal eating behaviors, altered growth patterns, and comorbid depression and anxiety. In
addition, emerging…
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