grant
Water Contaminants and Cardiovascular Risk: the Jackson Heart Study
Organization UNIVERSITY OF MISSISSIPPI MED CTRLocation JACKSON, UNITED STATESPosted 1 Sept 2024Deadline 31 Jul 2028
NIHUS FederalResearch GrantFY202521+ years oldAcidsAddressAdultAdult HumanAir PollutionApoplexyAreaArsenicBMIBMI percentileBMI z-scoreBiochemicalBioinformaticsBloodBlood PressureBlood Reticuloendothelial SystemBody mass indexBoilsBrain Vascular AccidentCardiovascularCardiovascular Body SystemCardiovascular DiseasesCardiovascular Organ SystemCardiovascular systemCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeCharacteristicsChemicalsChromiumChronicClinicalCommunitiesConsentCountyCr elementDataDeath RateDeteriorationDevelopmentDiabetes MellitusDisease OutcomeDisinfectantsDisinfectionEnvironmental ExposureEpidemiologic ResearchEpidemiologic StudiesEpidemiological StudiesEpidemiologyEpidemiology ResearchExposure toFatsFatty acid glycerol estersFurunclesFutureGC MSGCMSGas-Liquid-Mass Spectrometry ChromatographyGeographic AreaGeographic LocationsGeographic RegionGeographical LocationHealthHeart VascularHeart failureHepaticHydrogen OxideHypertensionICP-MSImmune responseIndividualInductively Coupled Plasma Mass SpectrometryInfrastructureInsulin ResistanceIntermediary MetabolismInterventionInvestigatorsJackson Heart StudyLeadLinkMaintenanceMass FragmentographiesMass FragmentographyMass Photometry/Spectrum AnalysisMass SpectrometryMass SpectroscopyMass SpectrumMass Spectrum AnalysesMass Spectrum AnalysisMass-Gas Chromatography SpectrometryMass-Gas Chromatography Spectrum AnalysisMeasuresMediatingMetabolicMetabolic ProcessesMetabolismMetalsMethodsMississippiMolecularMonitorNHLBINational Heart, Lung, and Blood InstituteNational Institutes of HealthObesityOutcomePFASParticipantPb elementPhenotypePlasticsPoliciesPoly-fluoroalkyl substancesPopulationPreparationPreventionProspective, cohort studyQuetelet indexRadioactive IsotopesRadioisotopesRadionuclidesRecordsResearch PersonnelResearch ResourcesResearchersResourcesRiskRisk FactorsSeasonsSourceStrokeSystemTechniquesTestingTimeTranslatingTriacylglycerolTriglyceridesTrihalomethanesUnited States National Institutes of HealthVascular Hypertensive DiseaseVascular Hypertensive DisorderVisceralWaterWater PollutantsWater SupplyWater contaminationadiposityadulthoodarsenicsboilbrain attackcardiac failurecardiometaboliccardiometabolismcardiovascular disease epidemiologycardiovascular disease riskcardiovascular disordercardiovascular disorder epidemiologycardiovascular disorder riskcardiovascular epidemiologycardiovascular healthcardiovascular riskcardiovascular risk factorcerebral vascular accidentcerebrovascular accidentcirculatory systemcohortcontaminated watercoronary artery calcium scoringcoronary calcium scoringcorpulencedesigndesigningdevelopmentaldiabetesdisease phenotypedrinking waterepidemiologicepidemiologic investigationepidemiologicalepidemiology studyexperienceexposomeexposomicsfasting plasma glucosegeographic siteheavy metal Pbheavy metal leadhigh blood pressurehost responsehyperpiesiahyperpiesishypertensive diseasehypertensive disorderimmune system responseimmunoresponseimprovedinnovateinnovationinnovativeinsulin resistantinsulin toleranceion trap mass spectrometrymass fragmentometrymetabolism measurementmetabolomicsmetabonomicsmortality ratemortality rationeglectnovelperfluorinated alkyl substancesperfluoroalkyl substancesperfluoroalkylated substancespolicy implicationpolyfluorinated alkyl substancespolyfluoroalkyl substancespreparationsprospectivepublic drinkingpublic health relevanceresponsestrokedstrokestoxicantwater contaminantwater monitoringwater qualitywater quality monitoringwater testing
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In Jackson, MS, decades of inadequate public water system infrastructure have resulted in disruptions to water access and diminished water quality. Jackson has been under a consent decree since 2012 for failing to meet operational and maintenance standards and continues to have boil water notices issued regularly, eliciting concern about the…
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