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VENTSAFE™ Life Saving Ventilation for the Treatment of ARDS

Organization VENTSAFE, INC.Location SAN FRANCISCO, UNITED STATESPosted 1 Sept 2024Deadline 31 Oct 2025 ⚠️
NIHUS FederalResearch GrantFY202521+ years old9-Octadecenoic AcidARDSAcute Respiratory DistressAcute Respiratory Distress SyndromeAdultAdult ARDSAdult HumanAdult RDSAdult Respiratory Distress SyndromeAir MovementsAirway failureAlveolarArteriesBarotraumaBlood Gas AnalysesBlood Gas AnalysisCO2Carbon DioxideCarbonic AnhydrideCessation of lifeClinicComputer AnalysisComputer softwareDa Nang LungDataDeathDevicesDysbarismFrequenciesGasesGeometryGoalsHigh-Frequency VentilationHistologyLifeLiquid substanceLungLung ParenchymaLung Respiratory SystemLung TissueLung damageMarketingMethodsMichiganModelingMorbidityMorbidity - disease rateO elementO2 elementOleic AcidsOxygenPalsyParalysedPatientsPatternPhasePhysicsPlegiaPopulationPreclinical TestingProcessRespiratory DiseaseRespiratory FailureRespiratory System DiseaseRespiratory System DisorderRiskSBIRSedation procedureShock LungSmall Business Innovation ResearchSmall Business Innovation Research GrantSoftwareStiff lungStructure of parenchyma of lungSystemTechnologyTestingTimeTranslatingTraumaTubeVentilatorVentilator-induced lung injuryVolutraumaadulthoodair flowairflowbench performance testingbench side testingbench testingbenchtop testingcis-9-Octadecenoic Acidcomputational analysescomputational analysiscomputer analysesconferenceconventionconventional therapyconventional treatmentdesigndesigningendotrachealfluidhigh riskimprovedliquidlung injurymortalitypandemicpandemic diseaseparalysisparalyticpig modelpiglet modelporcine modelpre-clinical testingpressurepreventpreventingprototypepulmonary damagepulmonary injurypulmonary tissue damagepulmonary tissue injuryrational designrespiratorysedationsummitswine modelsymposiasymposiumtime intervalventilationventilation induced lung injuryventilator associated lung injurywet lung

Applications closed.

Description preview

The goal of this Phase 1 SBIR project is to develop and test a bidirectional synchronous flow-controlled
ventilation system to improve oxygenation and ventilation in Acute Respiratory Distress Syndrome (ARDS).
Respiratory failure is a significant cause of mortality, leading to one million deaths annually worldwide1.
Respiratory pandemics are…

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