grant
Understanding the role of circadian clocks on healthy longevity
Organization NATIONAL INSTITUTE ON AGINGLocation UNITED STATES
NIHUS FederalResearch GrantFY2025AgingBehavioralBody TissuesCellular Immune FunctionChronic DiseaseChronic IllnessCircadian RhythmsDNA TherapyDietary InterventionDrug TherapyEnergy ExpenditureEnergy MetabolismExerciseGene ExpressionGene Transfer ClinicalGenetic InterventionGoalsHealthHealth StatusHourInterventionLength of LifeLevel of HealthLongevityLongevity PathwayMolecularNutrition InterventionsNutritional InterventionsNyctohemeral RhythmPersonal SatisfactionPharmacological TreatmentPharmacotherapyPhysiologicPhysiologicalPhysiologyProcessResearchRoleSystemTimeTissuesTwenty-Four Hour RhythmWorkage associated chronic conditionage associated chronic diseaseage associated chronic disorderage associated chronic health conditionage associated chronic illnessage related chronic conditionage related chronic diseaseage related chronic disorderage related chronic health conditionage related chronic illnesschronic disordercircadiancircadian clockcircadian pacemakercircadian processcircadian rhythmicitydaily biorhythmdiet interventiondrug interventiondrug treatmentfeedinggene repair therapygene therapygene-based therapygenetic therapygenomic therapyhallmarks of aginghealth levelimmune functioninsightlenslenseslife spanlife style interventionlifespanlifestyle interventionmultiomicsmultiple omicsnew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapy approachesnew treatment approachnew treatment strategynovelnovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapy approachpanomicspharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticspillars of agingpreventpreventingresponsesample collectionsocial rolespecimen collectionwell-beingwellbeing
Description preview
Our research shows that timed interventions (such as feeding and exercise) can synchronize circadian clocks in a tissue-specific manner. Understanding these distinct tissue responses is critical for uncovering how lifestyle interventions influence health status and well-being. Our findings highlight the importance of considering both the timing of…
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