grant
Tumor Microenvironment and Metastasis Program
Organization ALBERT EINSTEIN COLLEGE OF MEDICINELocation BRONX, UNITED STATESPosted 1 Jun 1997Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY2025AccelerationAddressAgingAnti-Cancer AgentsAntineoplastic AgentsAntineoplastic DrugsAntineoplasticsBasic ResearchBasic ScienceBiochemicalBiologic ModelsBiological MarkersBiological ModelsBiologyBody TissuesBrachydanio rerioBreastBreast Cancer Risk FactorCCSGCancer BiologyCancer Center Support GrantCancer DrugCancer PatientCancersCatchment AreaCell BodyCell Communication and SignalingCell SignalingCell SurvivalCell ViabilityCellsClinicalClinical MarkersClinical ResearchClinical StudyCollaborationsCommunitiesDanio rerioDetectable Residual DiseaseDevelopmentDiabetes MellitusDiseaseDisorderDisseminated Malignant NeoplasmEducationEducational aspectsEndocrine TherapyEpidemiological dataEpidemiology dataEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessExtravasationFosteringGeneticGoalsHNSCCHead and Neck CancerHead and Neck CarcinomaHead and Neck Squamous Cell CarcinomaHormonal TherapyHumanImaging technologyImmuneImmune mediated therapyImmunesImmunofluorescenceImmunofluorescence ImmunologicImmunologically Directed TherapyImmunotherapyIndividualInstitutionIntracellular Communication and SignalingInvestigatorsKnowledgeLeakageLife StyleLifestyleLungLung Respiratory SystemMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMalignant CellMalignant Head and Neck NeoplasmMalignant MelanomaMalignant NeoplasmsMalignant TumorMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMelanomaMetastasisMetastasizeMetastatic CancerMetastatic LesionMetastatic Malignant NeoplasmMetastatic MassMetastatic NeoplasmMetastatic TumorMetastatic breast cancerMetastatic/RecurrentMiceMice MammalsMinimal Residual DiseaseModel SystemModern ManMultiple MyelomaMurineMusNMR ImagingNMR TomographyNeoplasm MetastasisNeoplastic Disease Chemotherapeutic AgentsNew YorkNuclear Magnetic Resonance ImagingOncology GroupOrganOrganoidsOutputPathologyPathway interactionsPatient CarePatient Care DeliveryPlasma-Cell MyelomaPopulation ResearchPopulation-based researchPopulation-level researchPositionPositioning AttributePredispositionPreventionPrincipal InvestigatorProstateProstate GlandProstatic GlandRecurrenceRecurrentRelapseResearchResearch PersonnelResearchersResidual NeoplasmResidual TumorsResistanceResolutionSCCHNSYS-TXScienceSecondary NeoplasmSecondary TumorSightSignal TransductionSignal Transduction SystemsSignalingSiteSpillageSusceptibilitySystemic TherapyTechnologyTherapeuticTissuesTumor CellTumor-Specific Treatment AgentsVisionZebra DanioZebra FishZebrafishZeugmatographyanti-cancer drugbio-markersbiologic markerbiological signal transductionbiomarkerbreast cancer riskcancer cellcancer epidemiologycancer metastasiscancer microenvironmentcare for patientscare of patientscaring for patientschemotherapyclinical biomarkersclinical relevanceclinically relevantclinically useful biomarkersdevelopmentaldiabetesepidemiologic dataepigeneticallyhead and neck squamous carcinomahead and neck squamous cell cancerhead/neck cancerhormone therapyimage-based methodimaging methodimaging modalityimmune therapeutic approachimmune therapeutic interventionsimmune therapeutic regimensimmune therapeutic strategyimmune therapyimmune-based therapiesimmune-based treatmentsimmuno therapyin vivoinnovateinnovationinnovativeinsightintra-vital imagingintravital imagingmalignancymalignant head and neck tumormetastatic breast tumormetastatic mammary cancermetastatic mammary tumormulti-photonmyelomamyelomatosisneoplasm/cancerneoplastic cellnew drug targetnew druggable targetnew pharmacotherapy targetnew therapeutic targetnew therapy targetnovelnovel drug targetnovel druggable targetnovel pharmacotherapy targetnovel therapeutic targetnovel therapy targetpathwaypersonalization of treatmentpersonalized medicinepersonalized therapypersonalized treatmentprevent relapseprogenitor biologyprogenitor cell biologyprogramsrelapse preventionresidual diseaseresistantresolutionsstemstem and progenitor biologystem cell biologytargeted agenttherapeutic biomarkertherapeutic markertranslational opportunitiestranslational potentialtumor cell metastasistumor microenvironmentvisual function
Description preview
TUMOR MICROENVIRONMENT AND METASTASIS PROGRAM - PROJECT SUMMARY/ABSTRACT
The Tumor Microenvironment and Metastasis (TMM) Program is focused on investigating the genetic, epigenetic, biochemical, microenvironmental, and developmental pathways that drive dissemination, dormancy, and recurrence. These studies will identify novel therapeutic targets…
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