grant

Translational Research Core

Organization UNIVERSITY OF COLORADO DENVERLocation Aurora, UNITED STATESPosted 16 Sept 2011Deadline 31 Jul 2026
NIHUS FederalResearch GrantFY202519 year old19 years of age20 year old20 years of ageAddressAdherenceAdoptionAdult-Onset Diabetes MellitusAffectAgeAlaska IndianAlaska NativeAlaska Native groupAlaska Native individualAlaska Native peopleAlaska Native populationAlaska NativesAlaskan AmericanAlaskan IndianAlaskan NativeAlaskan Native AmericanAlaskan NativesAmericanAmerican IndianAmerican Indian PopulationAmerican Indian groupAmerican Indian individualAmerican Indian peopleAmerican IndiansAreaAttentionBlood PressureBudgetsCardiac DiseasesCardiac DisordersCaringCause of DeathCessation of lifeCholesterolClinicalCollaborationsColoradoCommunitiesCommunity OutreachCongressesConsultationsDeathDevelopmentDiabetes MellitusDiabetes preventionDiagnosisDiffusionDisparitiesDisparityESKDESRDEffectivenessEnd stage renal failureEnd-Stage Kidney DiseaseEnd-Stage Renal DiseaseEvaluationEvidence based practiceFacultyFundingGeneral PopulationGeneral PublicGlycohemoglobin AGlycosylated hemoglobin AGoalsHb A1Hb A1a+bHb A1cHbA1HbA1cHealthHealth Care SystemsHeart DiseasesHemoglobin A(1)IncidenceIndian Health ServiceIndigenous PopulationIndividualInterventionInvestigatorsKetosis-Resistant Diabetes MellitusKnowledgeLower ExtremityLower LimbMaturity-Onset Diabetes MellitusMeasurementMedicalMembrum inferiusMethodsMissionNIDDKNIDDMNational Institute of Diabetes and Digestive and Kidney DiseasesNative PeopleNative-BornNatureNon-Insulin Dependent DiabetesNon-Insulin-Dependent Diabetes MellitusNoninsulin Dependent DiabetesNoninsulin Dependent Diabetes MellitusOutcomePatient RecruitmentsPatientsPersonsPoliciesPopulationPremature MortalityPrevalencePreventionProviderQualitative ResearchRaceRacesRecommendationResearchResearch MethodologyResearch MethodsResearch PersonnelResearch ResourcesResearchersResourcesRisk FactorsRural PopulationRural groupRural peopleSatellite CentersServicesSisterSlow-Onset Diabetes MellitusStable Diabetes MellitusStructureT2 DMT2DT2DMTrainingTranslatingTranslational ResearchTranslational ScienceTranslationsType 2 Diabetes MellitusType 2 diabetesType II Diabetes MellitusType II diabetesUnited States Indian Health ServiceUniversitiesadult onset diabetesage 19 yearsage 20 yearsagesamputated limbbasebasescare costscommunity engagementcommunity settingconsultationdevelopmentaldiabetesdiabetes prevention programdiffuseddiffusesdiffusingdiffusionsdisease classificationdisorder classificationdisparity in healthdissemination scienceengagement with communitiesethnic minorityethnic minority groupethnic minority individualethnic minority peopleethnic minority populationevidence basefallshealth IThealth disparityhealth information technologyhealth literacyheart disorderhemoglobin A1cimplementation scienceimprovedinnovateinnovationinnovativeketosis resistant diabeteslimb amputationmaturity onset diabetesmortalitynineteen year oldnineteen years oldnosologyparticipant recruitmentparticipant retentionprematureprematurityprogramsracialracial backgroundracial minorityracial minority groupracial minority individualracial minority peopleracial minority populationracial originresearch and methodsresponserural individualtranslationtranslation researchtranslational investigationtreatment programtwenty year oldtwenty years of agetype 2 DMtype II DMtype two diabetes
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Full Description

TRANSLATION RESEARCH CORE: PROJECT SUMMARY
The Center for American Indian and Alaska Native Diabetes Translation Research (CAIANDTR) offers

resources locally, regionally, and nationally to advance a translational research agenda specific to AI/ANs, but

generalizable to other segments of the population—in particular racial/ethnic minorities and rural populations.

Its Translation Research Core: 1) Provides training, technical assistance, and consultation activities, delivered

through a Research Base of funded faculty -- drawn from the UC/AMC, but in this renewal expanded to sister

universities through an innovative network of Satellite Centers -- whose research either targets diabetes or is

translational in nature with clear potential for application to diabetes; and 2) Emphasizes community outreach

and engagement, with special attention to enhancing participant recruitment and retention; the cultural

adaptation of diabetes prevention and treatment interventions to improve effectiveness; health literacy

measurement and the development as well as evaluation of related materials and methods; health information

technologies that promote surveillance, increase patient knowledge, improve adherence to treatment

recommendations, and enhance compliance with standards of care; dissemination and implementation

science, notably individual, provider, and organizational factors that affect the diffusion and adoption of

evidence-based practices, programs, and policies related to diabetes prevention and treatment; and

sustainability that emphasizes the cost of caring for diabetes and related conditions, and that informs the

structure and financing of related services. The Translation Research Core rigorously evaluates the impact of

these activities on the capacity of other investigators to pursue scientifically meritorious diabetes translation

research specific to AI/ANs.

Grant Number: 5P30DK092923-15
NIH Institute/Center: NIH

Principal Investigator: Angela Brega

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