grant

Transgenic and Knockout Shared Resource

Organization MAYO CLINIC ROCHESTERLocation ROCHESTER, UNITED STATESPosted 25 Apr 1997Deadline 31 Aug 2030
NIHUS FederalResearch GrantFY2025AddressAdvisory CommitteesAllelesAllelomorphsAnimalsArizonaBreedingBudgetsCCSGCRISPR approachCRISPR based approachCRISPR methodCRISPR methodologyCRISPR techniqueCRISPR technologyCRISPR toolsCRISPR-CAS-9CRISPR-based methodCRISPR-based techniqueCRISPR-based technologyCRISPR-based toolCRISPR/CAS approachCRISPR/Cas methodCRISPR/Cas technologyCRISPR/Cas9CRISPR/Cas9 technologyCancer CauseCancer CenterCancer Center Support GrantCancer EtiologyCancersCas nuclease technologyChargeClinicClustered Regularly Interspaced Short Palindromic Repeats approachClustered Regularly Interspaced Short Palindromic Repeats methodClustered Regularly Interspaced Short Palindromic Repeats methodologyClustered Regularly Interspaced Short Palindromic Repeats techniqueClustered Regularly Interspaced Short Palindromic Repeats technologyCollaborationsCommunicationComplexComprehensive Cancer CenterConsultationsCryofixationCryopreservationDNAData AnalysesData AnalysisDedicationsDeoxyribonucleic AcidDerivationDerivation procedureDevelopmentDiseaseDisorderEmbryoEmbryonicExperimental DesignsFacultyFee-for-Service PlansFees for ServiceFertilization in VitroFloridaFundingGEM modelGEMM modelGene ExpressionGene TargetingGenerationsGenesGenetic EngineeringGenetic Engineering BiotechnologyGenetic Engineering Molecular BiologyGenetically Engineered MouseGenotypeHistopathologyHourHuman ResourcesInstitutionInvestigatorsJournalsKI miceKnock-in MouseKnock-outKnockoutLaboratory miceLeadershipMagazineMaintenanceMalignant NeoplasmsMalignant TumorManpowerMediatingMethodsMiceMice MammalsMouse StrainsMurineMusPoint MutationPreparationProceduresProcessPublicationsRecombinant DNA TechnologyRecoveryReporter GenesReportingResearchResearch PersonnelResearch ResourcesResearchersResource SharingResourcesScientific PublicationServicesSiteSpecialistSpinal ColumnSpineStructureTask ForcesTest-Tube FertilizationTestingTransgenic OrganismsVariantVariationVertebral columnWorkadvisory teambackbonecold preservationcold storageconditional knock-outconditional knockoutconsultationdata interpretationdesigndesigningdevelopmentaleggexperimentexperimental researchexperimental studyexperimentsgenetically engineeredgenetically engineered mouse modelgenetically engineered murine modelinsightinstrumentationinterestknockin micemalignancymembermodel designmouse genomemouse modelmurine modelmutantneoplasm/cancernew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapy approachesnew treatment approachnew treatment strategynovelnovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapy approachoperationoperationsoverexpressoverexpressionpersonnelpreparationspreventpreventingprogramspromoterpromotorscreeningscreeningssemen cryopreservationsperm cell cryopreservationsperm cryopreservationsperm freezingspermatozoa cryopreservationsuccesstooltransgene expressiontransgenic
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TRANSGENIC AND KNOCKOUT SHARED RESOURCE: ABSTRACT
The Transgenic and Knockout Shared Resource (TKOSR) of the Mayo Clinic Comprehensive Cancer Center

(MCCCC), led by Darren Baker (CGSM, MCR) since 2020, generates transgenic and gene-targeted mice for

researchers at Mayo Clinic in Rochester (MCR), Mayo Clinic in Arizona (MCA), and Mayo Clinic in…

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