grant

Topical treatment for burn pain by blocking cutaneous pain receptors.

Organization SERENTRIX, LLCLocation EXTON, UNITED STATESPosted 1 Aug 2024Deadline 31 Jul 2026
NIHUS FederalResearch GrantFY2025AccelerationAddressBurn injuryBurning PainBurnsBusinessesCutaneousDevelopmentFormulationFundingLicensingMarketingOpiate AddictionOpiate DependenceOpiatesOpioidPainPainfulPatientsPhasePreparednessReadinessResearchRiskSBIRSmall Business Innovation ResearchSmall Business Innovation Research GrantTRPV1TRPV1 geneTherapeuticTopical Drug AdministrationTopical applicationTranslatingapply topicallyburn therapyburn treatmentburnedcommercializationdeliver topicallydevelopmentaleffective therapyeffective treatmentimprovednew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapy approachesnew treatment approachnew treatment strategynon-narcotic analgesicnon-opiate analgesicnon-opioidnon-opioid analgesicnon-opioid therapeuticsnonnarcotic analgesicsnonopiate analgesicnonopioidnonopioid analgesicsnovelnovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapy approachopioid addictionopioid dependenceopioid dependentpain receptorperipheral painpublic health relevanceside effecttopical administrationtopical deliverytopical drug applicationtopical drug deliverytopical instillationtopical treatmenttransient receptor potential cation channel V1treat topically
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Full Description

Project Summary (Abstract)
Title: Technical and Business Assistance for Commercialization of Topical Treatment

for Burn Pain

This TABA request supports critical commercialization activities for the Phase I SBIR

project. The project focuses on the development of a first-in-class, non-opioid topical

formulation targeting TRPV1 and related cutaneous pain receptors, offering a novel

therapeutic approach for managing burn pain.

This support will directly enhance our readiness for Phase II funding and facilitate

downstream partnering or licensing opportunities. The proposed assistance is essential

to translating our research into a viable therapeutic product that addresses the

significant unmet need in treating burn-related pain.

Grant Number: 3R43GM150295-01A1S1
NIH Institute/Center: NIH

Principal Investigator: Kumaril Bhargava

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