grant
The spatial regulation of genetic and epigenetic integrity in Embryonic Stem cells
Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
Description preview
DNA is unstable and it can bear different types of lesions. We study breaks which affect both strands of DNA, the Double Strand Breaks (DSBs). DSBs can be repaired in an error free manner by copying the information from the sister chromatin using Homologous recombination. But they can also lead to deletions which can be either small if Non…
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