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The Sepsis ClinicAl Resource And Biorepository (SCARAB) Project
Organization VANDERBILT UNIVERSITY MEDICAL CENTERLocation NASHVILLE, UNITED STATESPosted 1 Jan 2022Deadline 31 Jan 2026 ⚠️
NIHUS FederalResearch GrantFY20250-11 years old21+ years oldARDSAcademic Medical CentersAcute Respiratory DistressAcute Respiratory Distress SyndromeAdultAdult ARDSAdult HumanAdult RDSAdult Respiratory Distress SyndromeAffectAgeAntibiotic AgentsAntibiotic DrugsAntibioticsBioinformaticsBiologic FactorBiologicalBiological FactorsBloodBlood PlasmaBlood Reticuloendothelial SystemBlood SampleBlood specimenCaringCensusesCessation of lifeChildChild YouthChildhoodChildren (0-21)ClinicalClinical DataCollectionCommunitiesComplementComplement ProteinsCoupledCritical IllnessCritically IllDNADa Nang LungDataData CollectionData SecurityData SetData awarenessDeathDeliriumDeoxyribonucleic AcidDevelopmentDistalDysfunctionElectronic Health RecordElementsEnrollmentEpidemiologic ResearchEpidemiologic StudiesEpidemiological StudiesEpidemiology ResearchFunctional disorderGene ExpressionGeneticHeterogeneityHospitalsHumanImageImmune responseIndividuals from minorityIndividuals of minorityInstitutionInvestigatorsLinkLiquid substanceLungLung Respiratory SystemManualsMechanical ventilationMedical RecordsMethodologyMethodsMicrobiologyMinority GroupsMinority PeopleMinority PopulationMinority individualMiscellaneous AntibioticModern ManMolecularNatural Language ProcessingObservation researchObservation studyObservational StudyObservational researchOn-Line SystemsOnline SystemsOrganOrgan failureOutcomeOutcome StudyPathologicPatientsPersonsPhasePhenotypePhysiopathologyPlasmaPlasma SerumProcessProspective StudiesProtocolProtocols documentationRegistriesReproducibilityResearchResearch DesignResearch PersonnelResearch ResourcesResearch SpecimenResearchersResourcesReticuloendothelial System, Serum, PlasmaRiskRisk FactorsSamplingSecuritySepsisSepsis SyndromeShock LungSocioeconomic FactorsSpecimenStiff lungStudy TypeSupportive TherapySupportive careSyndromeTestingTracheaTrachea ProperUniversity Medical CentersUrineValidationWhole Bloodadulthoodagesanti-microbialantimicrobialantisepsis treatmentaspiratebiobankbiologicbiological heterogeneitybiomed informaticsbiomedical informaticsbiorepositorycareerchildren with sepsisclinical phenotypecomplementationconcept mappingconcept mapsdata de-identificationdata deidentificationdata modelingdata sharingde-identified datadeidentified datadeliriousdesigndesigningdevelopmentalelectronic health care recordelectronic health medical recordelectronic health plan recordelectronic health registryelectronic medical health recordenrollepidemiologic investigationepidemiology studyethnic diversityethnically diverseexperiencefluidhost responseimagingimmune system responseimmunoresponseindexingindividuals with sepsisinformation securityinjuredinjury to organsinnovateinnovationinnovativeinterestinternet portalkidsliquidlung microbiomemechanical respiratory assistmechanically ventilatedmedical collegemedical schoolsmicrobialmodel of datamodel the datamodeling of the datamultidisciplinarymultiomicsmultiple omicsnatural language understandingnovelon-line portalonline computeronline portalorgan injurypanomicsparticipant enrollmentpathogenpathophysiologypatient enrollmentpatient populationpatients with sepsispediatricpediatric sepsispediatric septicpeople with sepsisphenotyping algorithmpredictive biological markerpredictive biomarkerspredictive markerpredictive molecular biomarkerprospectivepulmonary microbiomeracial diversityracially diverserespiratorysample collectionscale upschool of medicinescreeningscreeningssepsis caresepsis groupssepsis in childrensepsis interventionssepsis managementsepsis patientssepsis populationsepsis subjectssepsis therapeuticssepsis therapysepsis treatmentseptic childrenseptic groupseptic individualsseptic patientsseptic peopleseptic populationseptic subjectseptic therapyseptic treatmentsocio-demographicssocio-economicsocio-economic factorssocio-economicallysociodemographicssocioeconomicallysocioeconomicsspecimen collectionstudy designsubjects with sepsistargeted drug therapytargeted drug treatmentstargeted therapeutictargeted therapeutic agentstargeted therapytargeted treatmenttreat sepsisvalidationsventilationweb basedweb portalweb-based portalwet lungwindpipeyoungster
Applications closed.
Description preview
Sepsis is a major cause of organ failure and death in both children and adults around the world for which there
are no specific therapies other than antibiotics and supportive care. A major reason for the lack of targeted
therapies is our incomplete understanding of the genetic, environmental, microbial, socioeconomic and biologic
factors that…
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