grant

The role of nonlinearity and dispersion in spatiotemporal processing in the cochlea

Organization UNIVERSITY OF SOUTHERN CALIFORNIALocation Los Angeles, UNITED STATESPosted 7 May 2026Deadline 30 Apr 2031
NIHUS FederalResearch GrantFY2026AcousticsAddressAffectAlgorithmsAnimal ModelAnimal Models and Related StudiesAnimalsApicalAssayAuditoryAuditory PerceptionAuditory systemBehavioralBioassayBiological AssayCell Communication and SignalingCell SignalingClinicalCochleaCochlear OrganCommunicationComplexDataData AnalysesData AnalysisDevelopmentDoppler OCTEarEnsureEnvironmentExhibitsFrequenciesFutureGerbilsHearingHearing AidsHearing LossHumanHypoacusesHypoacusisImpairmentIndividualInternal EarIntracellular Communication and SignalingInvestigationKnowledgeLabyrinthLocationMath ModelsMeasurementMeasuresMechanicsMiceMice MammalsModelingModern ManMotionMurineMusMusicNoiseNon-linear DynamicNon-linear DynamicsNonlinear DynamicNonlinear DynamicsOCT TomographyOptical Coherence TomographyOrganOutputPatternProcessProcess AssessmentPropertyProxyPsychoacousticsRegulationResearchRoleSensorineural DeafnessSensorineural Hearing LossSensorySensory Hearing LossShapesSignal TransductionSignal Transduction SystemsSignalingSpeechSpeech IntelligibilitiesSpeech IntelligibilitySpeech SoundSpeedStimulusStructureTechnologyTestingTheoretic ModelsTheoretical modelTimeTransgenic MiceTravelanalogassistive hearing deviceassistive listening devicebasebasesbiological signal transductiondata interpretationdevelopmentaldiagnostic tooldysfunctional hearingfallsgood hearinghealthy hearinghearing amplificationhearing assistancehearing assistive devicehearing challengedhearing defecthearing deficienthearing deficithearing devicehearing difficultyhearing dysfunctionhearing impairmenthearing perceptionimprovedin silicoin vivoinner earinsightmathematic modelmathematical modelmathematical modelingmechanicmechanicalmodel of animalneuralnew diagnosticsnext generation diagnosticsnormal hearingnovel diagnosticsoptical Doppler tomographyoptical coherence Doppler tomographyotoacoustic emissionresponsesensorineural hearing impairmentsignal processingsimulationsocial rolesoundsound perceptionspatial and temporalspatial temporalspatiotemporaltranslation to humanstreatment strategyvibrationvocalization
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PROJECT SUMMARY
Human communication relies on speech sounds that exhibit complex spectral and temporal patterns, which must

be faithfully encoded by the cochlea—the sensory organ of hearing. While cochlear function has been exten-

sively studied using steady-state tones, much less is known about how the cochlea processes dynamic sounds

that vary…

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