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The Role of M1 Leg Area in Volitional and Stereotyped Control of the Lower Limb
Organization PROVIDENCE VA MEDICAL CENTERLocation PROVIDENCE, UNITED STATESPosted 1 Nov 2018Deadline 31 Aug 2025 ⚠️
VANIHUS FederalResearch GrantFY20252-dimensionalAddressAffectAmputationAmputeesAnimalsAreaArtificial ExtremitiesArtificial LimbsAttentionAutomobile DrivingAwardAxonBMIBMI percentileBMI z-scoreBehaviorBehavioralBody mass indexBrainBrain Nervous SystemBreathingCalibrationCancersCaringCell Communication and SignalingCell SignalingClassificationClinical ResearchClinical StudyCortical CordCustomCyclicityDataData SetDevelopmentDiseaseDisorderE-stimEconomicsElectric StimulationElectrocorticogramElectromyographyElectronicsEncephalonExtremitiesFailureFollow-Up StudiesFollowup StudiesFutureGaitHealthHomeHospital CostsHospitalization costHumanImplantIndividualIndustryIntentionIntracellular Communication and SignalingJointsKnowledgeLaboratoriesLeadLegLegs ParalysisLifeLimb ProsthesisLimb structureLimbsLocationLocomotionLower Extremities ParalysisLower ExtremityLower LimbLower Limbs ParalysisM mulattaM. mulattaMacacaMacaca mulattaMacaca rhesusMacaqueMalignant NeoplasmsMalignant TumorMapsMathMathematicsMedicalMedical RehabilitationMedulla SpinalisMembrum inferiusMembrum superiusMethodsMicroelectrodesMiniaturized ElectrodesModalityModelingModern ManMotionMotorMotor CortexMovementMuscleMuscle TissueNerve CellsNerve UnitNervous SystemNervous System InjuriesNervous System TraumaNervous System damageNeural CellNeurocyteNeurologic Body SystemNeurologic Organ SystemNeurological DamageNeurological InjuryNeurological traumaNeuronsNeurostimulation procedures of spinal cord tissueNon-TrunkPalpableParaplegiaPathway interactionsPatternPb elementPerformancePeriodicityPersonsPhasePhysiologic pulsePlayPopulationPositionPositioning AttributePrimatesPrimates MammalsProcessProsthesisProsthetic deviceProstheticsPublishingPulseQOLQuality of lifeQuetelet indexRehabilitationRehabilitation therapyReportingRespiratory AspirationRespiratory InspirationRhesus MacaqueRhesus MonkeyRhythmicityRoboticsRoleRotationSi elementSignal TransductionSignal Transduction SystemsSignalingSiliconSpinalSpinal ColumnSpinal CordSpinal Cord StimulationSpinal Cord TraumaSpinal InjuriesSpinal TraumaSpinal cord injuredSpinal cord injurySpineStereotypingSystemSystematicsTechnologyTherapeuticTimeTrainingTranslationsTransmissionTraumaTraumatic MyelopathyUnited StatesUnited States Department of Veterans AffairsUnited States Veterans AdministrationUpper ExtremityUpper LimbUpper limb movementValidationVascular DiseasesVascular DisorderVertebral columnVeteransVeterans AdministrationVeterans AffairsWalkingWorkamputated limbbackbonebiological signal transductionblood vessel disorderbody movementbrain controlbrain implantbrain machine interfaceclinical translationclinically translatablecustomsdata to traindataset to traindesigndesigningdevelopmentaldisableddrivingeconomicelectrocorticographyelectronicelectronic deviceelectrostimulationfeature extractionfirst in manfirst-in-humanflexibilityflexiblefootfunctional restorationheavy metal Pbheavy metal leadhomeshuman studyinsightinspirationinstrumentkinematic modelkinematicslimb amputationlimb losslimb movementlocomotor taskslost limbmalignancymilitary operationmilitary veteranmotor controlmotor rehabmotor rehabilitationmotor rehabilitative therapymuscularneoplasm/cancerneuralneural implantneuro-prostheticneuronalneuroprosthesisneuroprostheticneurotechnologyneurotraumanon-human primatenonhuman primatepalpable diseaseparaplegicpathwaypre-clinicalpreclinicalprosthetic limbrehab therapyrehabilitativerehabilitative therapyrestore functionrestore functionalityrestore lost functionsensorsocialsocial rolespatial and temporalspatial temporalspatiotemporalspine injurytechnology platformtechnology systemtooltraining datatranslationtransmission processtreadmilltwo-dimensionalvalidationsvascular dysfunctionvasculopathyvertebral injuryveteran populationwirelesswireless data transferwireless data transmission
Applications closed.
Description preview
In the healthy nervous system, the development of intention and motor execution is a dynamic and highly
distributed process that originates in the brain. The intended action is transmitted along the axonal super
highway to smart circuits in the spinal cord that transform the descending command into coordinated patterns
of muscle activation. While…
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