grant
The relationship between HIV exposure, contact networks, and TB in children under 5 years old
Organization BOSTON MEDICAL CENTERLocation BOSTON, UNITED STATESPosted 20 Aug 2024Deadline 31 Jul 2029
NIHUS FederalResearch GrantFY20250-11 years old21+ years old5 year old5 years of ageAIDS VirusAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAdultAdult HumanAffectAgeAirAutomobile DrivingBirthBostonCare GiversCareer Development AwardsCareer Development Awards and ProgramsCareer Development Programs K-SeriesCaregiversCessation of lifeChildChild YouthChildhoodChildren (0-21)Cohort StudiesCommunicable Disease Contact TracingCommunicable DiseasesComplexConcurrent StudiesContact TracingDataData BasesDatabasesDeathDetectionDiagnosisDiseaseDisorderEducational workshopEnrollmentEnvironmentEpidemiologic ResearchEpidemiologic StudiesEpidemiological StudiesEpidemiology ResearchEthnographyEvolutionFaceFoundationsFutureGoalsHIVHIV InfectionsHIV anti-retroviralHIV/MtbHIV/TBHIV/mycobacterium tuberculosisHIV/tuberculosisHTLV-III InfectionsHTLV-III-LAV InfectionsHealthHouseholdHuman Immunodeficiency VirusesHuman T-Lymphotropic Virus Type III InfectionsIllicit DrugsIncidenceIndividualInfectionInfectious Disease Contact TracingInfectious DiseasesInfectious DisorderInvestigatorsK-AwardsK-Series Research Career ProgramsLAV-HTLV-IIILifeLiquid substanceLymphadenopathy-Associated VirusM tuberculosis infectionM. tb infectionM. tuberculosis infectionM. tuberculosis/HIVM.tb infectionM.tuberculosis infectionMTB infectionMeasuresMedical centerMentorsMentorshipMeta-AnalysisMorbidityMorbidity - disease rateMycobacterium tuberculosis (MTB) infectionMycobacterium tuberculosis infectionNIAIDNICHDNational Institute of Allergy and Infectious DiseaseNational Institute of Child Health and Human DevelopmentNetwork AnalysisParturitionPathway AnalysisPersonsPhysiciansPlayPoliciesPredispositionPrevalenceProspective StudiesProspective, cohort studyProvinceQuestionnairesReportingResearchResearch Career ProgramResearch DesignResearch PersonnelResearch SupportResearchersRiskRisk FactorsRoleScientistSmokeSocial EnvironmentSocial NetworkSouth AfricaStructureStudy TypeSurvival AnalysesSurvival AnalysisSusceptibilityTB infectionTestingTrainingTransmissionTuberculosisUncertaintyUniversitiesVirus-HIVWorkshopadulthoodage 5 yearsagesantiretroviral therapyantiretroviral treatmentarmco-infectioncohortcoinfectiondata basedisseminated TBdisseminated tuberculosisdoubtdrivingearly childhoodenrollepidemiologic investigationepidemiology studyethnographicethnographic methodexperiencefacesfacialfive year oldfive years of agefluidfluidityhigh risk grouphigh risk individualhigh risk peoplehigh risk populationillicit drug useimprovedindexingindividual patientinfection due to Mycobacterium tuberculosisinnovateinnovationinnovativeinsightkidsliquidmembermenmortalitynovelpandemicpandemic diseasepediatricperinatal HIVpreventpreventingprospectiverecruitrisk mitigationskillssocialsocial climatesocial contextsocial epidemiologysocial rolesocioenvironmentsocioenvironmentalstudy designtherapy adherencetherapy compliancetransmission processtuberculosis infectiontuberculous spondyloarthropathyyoungster
Description preview
PROJECT SUMMARY / ABSTRACT
More than 200,000 children die each year from TB, of whom 80% are <5 years old. HIV is a leading risk factor
for TB disease in both children and adults. Despite longstanding reliance upon household contact tracing to
identify children with TB, recent estimates suggest that only 10-30% of children with TB are infected…
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