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The Next Wave of Asthma Therapeutics
Organization BIOTHERAPEUTICS, INC.Location Blacksburg, UNITED STATESPosted 1 Feb 2025Deadline 31 Jan 2026 ⚠️
NIHUS FederalResearch GrantFY2025(TNF)-α3-10CAMCF-IAccelerationAffectAirway DiseaseAirway ResistanceAllergic DiseaseAllergic asthmaAllergyAnimal ModelAnimal Models and Related StudiesAnti-InflammatoriesAnti-Inflammatory AgentsAnti-inflammatoryAssayAsthmaAutoimmuneAutoimmune DiseasesB cell differentiation factorB cell stimulating factor 2B-Cell Differentiation FactorB-Cell Differentiation Factor-2B-Cell Stimulatory Factor-2BCDFBSF-2BSF2BenchmarkingBenignBest Practice AnalysisBindingBioassayBiological AssayBiological Response Modifier TherapyBiological TherapyBiotechBiotechnologyBlood NeutrophilBlood Polymorphonuclear NeutrophilBronchial AsthmaCD4 CellsCD4 Positive T LymphocytesCD4 T cellsCD4 helper T cellCD4 lymphocyteCD4+ T-LymphocyteCD4-Positive LymphocytesCDw128bCMKAR2CTLA-8CTLA-8 GeneCTLA8CTLA8 GeneCXCL8CXCR2CachectinCell BodyCell Communication and SignalingCell SignalingCellsChemotactic CytokinesChronicClinical TrialsCo-StimulatorCo-cultureCocultivationCocultureCoculture TechniquesComputer ModelsComputerized ModelsCostimulatorCytotoxic T-Lymphocyte-Associated Antigen 8Cytotoxic T-Lymphocyte-Associated Antigen 8 GeneCytotoxic T-Lymphocyte-Associated Serine Esterase 8Cytotoxic T-Lymphocyte-Associated Serine Esterase 8 GeneDevelopmentDiseaseDisorderDoseDrugsEarly-Stage Clinical TrialsEpidermal Thymocyte Activating FactorEpithelial CellsEvaluationExtrinsic asthmaFlow CytofluorometriesFlow CytofluorometryFlow CytometryFlow MicrofluorimetryFlow MicrofluorometryGCP1Genus HippocampusGoalsGoblet CellsHPGFHealth CareHepatocyte-Stimulating FactorHistopathologyHomologous Chemotactic CytokinesHouse Dust MitesHousedust MitesHuB219HumanHybridoma Growth FactorHyperplasiaHyperplasticIFN-beta 2IFNB2IL-17IL-17 GeneIL-17AIL-17A GeneIL-2IL-6IL-8IL17IL17 ProteinIL17 geneIL17AIL17A GeneIL2 ProteinIL6 ProteinIL8IL8 geneIL8R2IL8RBIL8RB geneImmuneImmunesImmunologyImmunomodulationInflammationInflammatoryIntercrinesInterleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8)Interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8) GeneInterleukin 17 PrecursorInterleukin 17 Precursor GeneInterleukin 2Interleukin 2 PrecursorInterleukin IIInterleukin-17Interleukin-2Interleukin-6Interleukine 2Interleukine 2 PrecursorInterleukine IIIntermediary MetabolismIntracellular Communication and SignalingK60Knock-outKnockoutLEP-RLEPR ProteinLegal patentLigandsLigaseLigase GeneLipopolysaccharidesLungLung Respiratory SystemLymphocyte Mitogenic FactorMGF proteinMGI-2MGSNF proteinMacrolidesMacrophage-Derived TNFMarketingMarrow NeutrophilMedicalMedicationMetabolicMetabolic ProcessesMetabolismMethodsMethotrexateMethotrexate MethylaminopterinMethotrexatumMetotrexatoMiceMice MammalsMitogenic FactorModelingModern ManMolecular InteractionMonocyte-Derived TNFMurineMusMyeloid Differentiation-Inducing ProteinNeutrophil InfiltrationNeutrophil RecruitmentNeutrophilic GranulocyteNeutrophilic InfiltrateNeutrophilic LeukocyteOB ReceptorOB-ROralOutcomeOvalbuminPBMCPatentsPathway interactionsPeripheral Blood Mononuclear CellPersonsPharmaceutical PreparationsPhasePhase 1 Clinical TrialsPhase I Clinical TrialsPhenotypePlasmacytoma Growth FactorPolymorphonuclear CellPolymorphonuclear LeukocytesPolymorphonuclear NeutrophilsPre-Clinical ModelPreclinical ModelsProgram DevelopmentProliferatingPublic HealthPyroglyphidaeReceptor ProteinRegulatory T-LymphocyteRiskRouteSBIRSCYB8SIS cytokinesSTAT5STAT5ASTAT5A geneSTAT5a Transcription FactorSafetySeahorseSignal Transducer and Activator of Transcription 5ASignal TransductionSignal Transduction SystemsSignalingSmall Business Innovation ResearchSmall Business Innovation Research GrantStat5 proteinStat5a proteinStat5alpha proteinSynthetasesT cell growth factorT-Cell Growth FactorT-Cell Stimulating FactorT4 CellsT4 LymphocytesTNFTNF ATNF AlphaTNF geneTNF-αTNFATNFαTSG-1Target PopulationsTherapeuticThymocyte Stimulating FactorTreatment EfficacyTregTumor Necrosis FactorTumor Necrosis Factor-alphaantagonismantagonistasthma modelasthma patientasthmatic patientatopic asthmaautoimmune conditionautoimmune disorderautoimmunity diseaseb-ENAPbenchmarkbiological signal transductionbiological therapeuticbiological treatmentbiologically based therapeuticsbiotherapeuticsbiotherapybronchial epitheliumchemoattractant cytokinechemokinecommercial applicationcomputational modelingcomputational modelscomputer based modelscomputerized modelingcytokinedevelopmentaldiet-associated obesitydiet-induced obesitydiet-related obesitydisease riskdisorder riskdrug candidatedrug/agentextrinsic allergic asthmaflow cytophotometryguinea pig modelhigh riskimmune modulationimmune regulationimmunologic reactivity controlimmunomodulatoryimmunoregulationimmunoregulatoryimprovedinhibitorinnovateinnovationinnovativeinterferon beta 2intervention efficacylanthionineleptin receptorleptin-binding proteinmammary gland factormammary gland-specific nuclear factormetabolic profilemodel of animalmouse modelmurine modelneutrophilnew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapeuticsnew therapynew therapy approachesnew treatment approachnew treatment strategynext generation therapeuticsnovelnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapeuticsnovel therapynovel therapy approachobese asthmaobesity-associated asthmaobesity-related asthmapathwaypatient subclasspatient subclusterpatient subgroupspatient subpopulationspatient subsetspatient subtypesphase I protocolpublic health relevancereceptorregulatory T-cellsresponseside effectsignal tranducer and activator of transcription 5small molecule therapeuticssteroid addictionsteroid dependencesuccesssynergismtherapeutic candidatetherapeutic efficacytherapy efficacy
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Description preview
The Next Wave of Asthma Therapeutics
Biotherapeutics Inc (BTI) is an emerging biotech company that synergistically combines the power of advanced
computational modeling with translational experimentation to accelerate the development of novel products for
precision immunology. We have filed patent applications related to novel methods of…
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