grant

The Impact of an Evidence-Based, Behavioral Cervical Cancer Screening Intervention among Women Living with HIV in Ghana (HOPE-inG): A Type 2 Hybrid Effectiveness Implementation Trial

Organization BAYLOR UNIVERSITYLocation WACO, UNITED STATESPosted 1 Sept 2024Deadline 31 Aug 2029
NIHUS FederalResearch GrantFY20252 arm RCT2 arm randomized control trial2 arm randomized controlled trial2-arm trialAIDSAIDS VirusAcquired Immune DeficiencyAcquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome VirusAddressAdoptionBehaviorBehavioralCancer BurdenCervical CancerCervical Cancer ScreeningCervix CancerClinicClinicalCollaborationsCommunicationCommunitiesControl GroupsCost AnalysesCost AnalysisCountryCoupledDataEffectivenessEligibilityEligibility DeterminationEnrollmentEvaluationExploration, Preparation, Implementation, and SustainabilityExploration, Preparation, Implementation, and SustainmentFamilyFeedbackFemale HealthFundingGhanaGold CoastHIVHPVHPV-High RiskHealth CareHealth Care FacilityHealth Care ProvidersHealth FacilitiesHealth PersonnelHealth systemHigh PrevalenceHigh Risk Oncogenic HPVHigh risk HPVHigh risk Human PapillomavirusHigh risk Human papilloma virusHomeHospitalsHuman Immunodeficiency VirusesHuman Papilloma VirusHuman PapillomavirusHybridsIndigenousIndividualInfectious Human Wart VirusInfrastructureInterventionInterviewLAV-HTLV-IIILMICLeadershipLymphadenopathy-Associated VirusMalignant Cervical NeoplasmMalignant Cervical TumorMalignant Neoplasm of the CervixMalignant Tumor of the CervixMalignant Tumor of the Cervix UteriMalignant Uterine Cervix NeoplasmMalignant Uterine Cervix TumorMalignant neoplasm of cervix uteriMeasurementMethodsModelingNational Cancer BurdenOutcomeParticipantPatient RepresentativePatientsPenetrationPhasePopulationPreparationPrevention educationProtocol ScreeningProviderRandomizedRandomized, Controlled TrialsReportingResearchResearch ResourcesResourcesRiskSamplingScreening for cancerScreening procedureSelf EfficacySensitivity and SpecificitySiteSocial supportSurvey InstrumentSurveysSystemTeaching HospitalsTechniquesTestingTrainingTranslatingTranslationsUterine Cervix CancerVariantVariationVirus-HIVWomanWomen's Healtharmassess costassess effectivenesscare facilitiescervical cancer early detectioncervical cancer preventioncervical screeningcostcost assessmentcost evaluationdetermine effectivenessearly cancer detectioneffectiveness and implementation trialeffectiveness assessmenteffectiveness evaluationeffectiveness researcheffectiveness-implementation RCTeffectiveness-implementation randomized control trialeffectiveness-implementation randomized controlled trialeffectiveness/implementation hybrid studyeffectiveness/implementation hybrid trialeffectiveness/implementation studyeffectiveness/implementation trialefficacy studyenrollevaluate costevaluate effectivenessevidence baseexamine costexamine effectivenessgroup interventionhealth care personnelhealth care workerhealth providerhealth workforcehomeshrHPVhybrid type 2 trialhybrid type II trialimplementation interventionimplementation measuresimplementation outcomesimplementation researchimplementation strategyimplementation/effectivenessinnovateinnovationinnovativeinterestlow and middle-income countriesmedical personnelmedically under servedmedically underservedparticipant enrollmentpatient enrollmentprecancer cervical detectionpreparationsprimary outcomeprogramsrandomisationrandomizationrandomized control trialrandomly assignedrecruitresearch into practiceresearch to practiceresponseroutine practicescale upscreeningscreening cancer patientsscreening toolsscreeningssocial support networkstrategies for implementationsuccesstooltranslationtreatment providertwo arm RCTtwo arm randomized control trialtwo arm randomized controlled trialtwo-arm trialuptakewart virus
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ABSTRACT
Over 69,000 women living with HIV, (WLWH) in Ghana have a six-fold increased risk of developing cervical

cancer1 and require early and frequent cervical cancer screening (CCS).2-4 However, available data in Ghana

show that the CCS rate among eligible women is as low as 2.7%, and there is no evidence that WLWH screen

at higher rates.5 In…

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