grant
The Effectiveness of Automated Multimodal Imaging in High Grade Squamous Intraepithelial Lesions (HSIL) Diagnosis for People Living with HIV: An International Trial
Organization BAYLOR COLLEGE OF MEDICINELocation HOUSTON, UNITED STATESPosted 18 Dec 2018Deadline 31 Aug 2029
NIHUS FederalResearch GrantFY2025AI AugmentedAI assistedAI basedAI drivenAI enhancedAI integratedAI poweredAI systemAIDS VirusAccuracy of DiagnosisAcetic AcidsAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusActive Follow-upAddressAdministratorAdoptionAgingAlgorithmic AnalysesAlgorithmic AnalysisAnalAnal CancerAnalyses of AlgorithmsAnalysis of AlgorithmsAnusAnus CancerApplication ContextAreaArtificial IntelligenceArtificial Intelligence enhancedAugmented by AIAugmented by the AIAugmented with AIAugmented with the AIBiopsyBrazilCancersCervical CancerCervixCervix CancerCervix UteriClinicalClinical TrialsColposcopyCommunitiesComputer AssistedComputer ReasoningComputer softwareCoupledDataData BanksDatabanksDecision MakingDetectionDevelopmentDiagnosisEarly treatmentEffectivenessEnsureEnvironmentEpidermoid Cell CancerEpitheliumEvaluationFutureGeneral PopulationGeneral PublicHIVHIV infected menHIV positive menHIV+ menHealth CareHistologicHistologicallyHistologyHistopathologyHuman Immunodeficiency VirusesImageImage AnalysesImage AnalysisIncidenceInternationalLAV-HTLV-IIILesionLow incomeLow-resource areaLow-resource communityLow-resource environmentLow-resource regionLow-resource settingLymphadenopathy-Associated VirusMSMMachine IntelligenceMachine LearningMales living with HIVMalignant Anal NeoplasmMalignant Anal TumorMalignant Cervical NeoplasmMalignant Cervical TumorMalignant Epidermoid Cell NeoplasmMalignant Epidermoid Cell TumorMalignant Neoplasm of the CervixMalignant NeoplasmsMalignant Squamous Cell NeoplasmMalignant Squamous Cell TumorMalignant TumorMalignant Tumor of the AnusMalignant Tumor of the CervixMalignant Tumor of the Cervix UteriMalignant Uterine Cervix NeoplasmMalignant Uterine Cervix TumorMalignant neoplasm of anusMalignant neoplasm of cervix uteriMan who have sex with ManMen with HIVMorphologyMultimodal ImagingMultimodal MLMultimodal machine learningNeoplasmsOptical BiopsyOralOutcomes ResearchParticipantPatientsPerformancePersonsPopulationPredictive ValuePreventionProceduresProviderReportingResearch ResourcesResolutionResource-constrained areaResource-constrained communityResource-constrained environmentResource-constrained regionResource-constrained settingResource-limited areaResource-limited communityResource-limited environmentResource-limited regionResource-limited settingResource-poor areaResource-poor communityResource-poor environmentResource-poor regionResource-poor settingResourcesRiskScreening for cancerSkinSoftwareSpecificitySquamous Cell CancersSquamous Cell Intraepithelial NeoplasiaSquamous intraepithelial lesionStomachTechnologyTimeTrainingUterine CervixUterine Cervix CancerVirus-HIVVisitactive followupaged groupaged groupsaged individualaged individualsaged peopleaged personaged personsaged populationaged populationsaging populationanal squamous cell carcinomaarmartificial intelligence assistedartificial intelligence augmentedartificial intelligence basedartificial intelligence drivenartificial intelligence integratedartificial intelligence poweredcancer invasivenesscohortcomputer aidedcontextual factorscostdata depositorydata repositorydata set repositorydataset repositorydetermine efficacydevelopmentaldiagnostic accuracyearly cancer detectionearly therapyefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationendomicrosopeenhanced with AIenhanced with Artificial Intelligenceevaluate efficacyexamine efficacyexperiencefollow upfollow-upfollowed upfollowupgastricglobal healthhigh riskimage evaluationimage interpretationimagingimaging approachimaging based approachimaging platformimplementation facilitationimprovedmachine based learningmachine learned algorithmmachine learning algorithmmachine learning based algorithmmalignancyman living with HIVmen diagnosed with HIVmen having sex with menmen infected with HIVmen living with HIVmen who have sex with menmen who have sex with other menmetermicroendoscopemulti-modal imagingmulti-modalitymulti-modality imagingmultimodal learningmultimodalitymultimodality imagingneoplasianeoplasm/cancerneoplastic growthnovelpoint of carepoint-of-care diagnosticspopulation agingpractice settingprecancerprecancerouspremalignantpreventpreventingprimary care providerprimary outcomeproviders from primary careproviders of primary careresearch studyresolutionsscreeningscreening cancer patientsscreeningssecondary outcomeskillsstandard of caretech developmenttechnology developmenttheoriestool
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Abstract: Squamous cell cancer of the anus (SCCA) is increasing in the aging cohort of people living with HIV
(PWH), who are at 40-80x higher risk for SCCA than the general population. The increase in invasive anal cancer,
and its precursor, high-grade squamous intraepithelial lesions (HSIL), has led to a focus on prevention in PWH.
The Anal…
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