grant

Testing the developmental theory of ageing: from genes to populations

Organization UKRILocation United Kingdom
UKRIUK ResearchGrantActive
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Why do organisms age? The decline in the force of natural selection with age leads to accumulation of late-acting deleterious alleles (‘mutation accumulation’) and selection for alleles whose effects of fitness are beneficial in early-life but detrimental in late-life (‘antagonistic pleiotropy’). However, these population genetic models do not…

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