grant

Telomere End-Protection and the Anti-Checkpoint

Organization Cleveland Clinic FoundationLocation CLEVELAND, United StatesPosted 1 Sept 2025Deadline 31 Aug 2028
NSFUS FederalResearch GrantScience FoundationOH
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Description preview

The DNA of organisms from yeast to humans is packaged in linear chromosomes, the ends of which are called telomeres. When chromosomes are broken, the broken ends can be degraded or fused with other chromosomes to cause mutations and diseases such as cancer. Broken chromosomes and telomeres both present DNA ends, but telomeres have special DNA…

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Telomere End-Protection and the Anti-Checkpoint — Cleveland Clinic Foundation | United States | Sept 2025 | Dev Procure