Targeting complement component 5 to reduce neuroinflammation and treat Alzheimer's disease with new chemical and microscopy tools.

Alzheimer's disease (AD) is a leading cause of late-life disability and death, affecting millions worldwide. A hallmark of the disease are amyloid plaques combined with inflammation in the brain. There is growing evidence that part of the innate immune system, the complement system, may be key to reducing neuroinflammation in neurodegenerative…