Targeted Disruption of MDM2 Dimerisation as a Novel Approach to Treating High-Risk Neuroblastoma
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Accounting for greater than 20% of neonatal cancers, neuroblastoma (NB) represents the most common extracranial paediatric malignancy [1]. An embryonal tumour, NB arises from the sympathetic nervous system and is responsible for 15% of paediatric cancer mortality. Despite significant advances in NB diagnosis and treatment, high-risk NB (i.e.,…
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