grant
Systems Biology of Early Atopy (SUNBEAM) Analysis and Bioinformatics Center
Organization ICAHN SCHOOL OF MEDICINE AT MOUNT SINAILocation NEW YORK, UNITED STATESPosted 8 Dec 2022Deadline 30 Nov 2028
NIHUS FederalResearch GrantFY20260-11 years old21+ years oldAdultAdult HumanAffectAllergicAllergic DiseaseAllergic to foodAllergyAllergy to foodAnaphylactic ReactionAnaphylactic ShockAnaphylaxisAngioedemaAngioneurotic EdemaAreaAssayAtopic AllergyAtopic DermatitisAtopic EczemaAtopic NeurodermatitisAwardBioassayBioinformaticsBiologicalBiological AssayBiological MarkersBiologyBirthCardiovascularCardiovascular Body SystemCardiovascular Organ SystemCardiovascular systemChildChild YouthChildren (0-21)ChronicClinicalClinical ManagementCollectionCommunicationComplexComputational BiologyDataData ScienceDevelopmentDiagnosisDimensionsDiseaseDisorderDisseminated NeurodermatitisDistressEmotionalEnrollmentEnsureFathersFoodFood AllergyFood HypersensitivityFundingFutureGeneral PopulationGeneral PublicGeneticGenomeGiant UrticariaGoalsHealthHeart VascularHivesImmuneImmunesImmunologistImpairmentIndividualInfrastructureIngestionIntervention StrategiesInvestigatorsKnowledgeLifeMolecularNIAIDNational Institute of Allergy and Infectious DiseaseNational Institutes of HealthNutritionParticipantParturitionPhenotypePhysiciansPoliciesPregnant WomenPreventionProceduresProteomeQOLQuality of lifeQuincke's EdemaResearchResearch ActivityResearch PersonnelResearchersRiskRisk FactorsRoleScientistSkinSymptomsSystemSystems BiologyTechnologyTimeUnited States National Institutes of HealthUrticariaVisualizationadulthoodallergic dermatitisallergic eczemaatopic triadatopybio-markersbiobankbiologicbiologic markerbiological heterogeneitybiological systemsbiomarkerbiorepositorybirth cohort studybirth cohort surveycirculatory systemcohortcomputer biologydata integrationdesigndesigningdevelopmentalenrollentire genomeexpectant motherexpectant womenexpectationexpecting motherexpecting womenexperiencefood antigenfull genomegastrointestinalglobal gene expressionglobal transcription profilehigh dimensionalityimprovedindividuals who are pregnantingestinnovateinnovationinnovativekidslipidomemachine learning based modelmachine learning modelmetabolomemetabonomemicrobiomemulti-scale datamultiomicsmultiple omicsmultiscale datanew markernovelnovel biomarkernovel markerpanomicspeople who are pregnantpregnant femalespregnant motherspregnant peoplepregnant populationsrespiratoryrisk sharingsocial rolesuccessthose who are pregnanttooltranscriptomewhole genomewomen who are pregnantyoungster
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PROJECT SUMMARY
Food allergy (FA) and atopic dermatitis (AD) are common chronic conditions of atopy affecting 10% and 20%
of children, respectively. Individuals with FA are at daily risk for potentially life-threatening hives, angioedema,
respiratory difficulty, cardiovascular compromise, gastrointestinal distress, and/or anaphylaxis following…
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