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Synaptic plasticity underlying sex differences in aggression reward

Organization UNIVERSITY OF MINNESOTALocation MINNEAPOLIS, UNITED STATESPosted 1 Dec 2023Deadline 30 Nov 2025 ⚠️
NIHUS FederalResearch GrantFY2025AggressionAggressive behaviorAutomobile DrivingBathingBathsBehaviorBehavior assessmentBehavioralBrainBrain Nervous SystemCalciumCalcium Ion SignalingCalcium SignalingCell BodyCellsCustomDendritic SpinesDevelopmentDifferences between sexesDiffers between sexesE-stimElectric StimulationElectrophysiologyElectrophysiology (science)EncephalonEndocrine Gland SecretionFemaleFiberGlutamate ReceptorGlutamatesGoalsGolden HamstersGolden Syrian HamstersHomeHormonesHypothalamic structureHypothalamusImageInvestigatorsL-GlutamateLeadLearningLoveMaintenanceMeasuresMediatingMediatorMental HealthMental HygieneMental disordersMental health disordersMentorsMentorshipMesocricetus auratusModelingMotivationNatureNerve CellsNerve UnitNeural CellNeural TransmissionNeurobiologyNeurocyteNeuronsNeurophysiology / ElectrophysiologyNucleus AccumbensOcytocinOutcomeOxytocinParaventricular Hypothalamic NucleusPathway interactionsPb elementPhasePhotometryPhysiologicPhysiologicalPhysiologyPostdocPostdoctoral FellowPrefrontal CortexPropertyPsychiatric DiseasePsychiatric DisorderPsychological HealthPublishingRecombinant OxytocinResearchResearch AssociateResearch PersonnelResearch ResourcesResearchersResourcesRewardsRoleRunningSex DifferencesSexual differencesSliceSocial InteractionSourceSynapsesSynapticSynaptic TransmissionSynaptic plasticitySyrian HamstersTechniquesTestingTherapeuticTherapeutic HormoneTherapeutic InterventionTrainingTransmissionbehavior measurementbehavioral assessmentbehavioral measurebehavioral measurementbehavioral plasticitycareerclinical translationclinically translatablecombatcomparing females and malescomparing women and menconditioned place preferencecustomsdendrite spinedensitydesigndesigningdevelopmentaldrivingelectrophysiologicalelectrostimulationexperiencefemales compared to malesfemales compared with malesfemales versus malesfemales vs. malesglutamatergicgraduate schoolheavy metal Pbheavy metal leadhomeshypothalamicimagingimprovedin vivointervention therapymalemental illnessmotivated behaviorneural mechanismneurobiologicalneurobiological mechanismneuromechanismneuron componentneuronalnoveloptogeneticsparaventricular nucleuspatch clamppathwayplace conditioningpost-docpost-doctoralpost-doctoral traineepreferencepreservationprogramspsychiatric illnesspsychological disorderreceptor expressionresearch associatesresearch facilityrole modelsexsex based differencessex-dependent differencessex-related differencessex-specific differencesskill acquisitionskill developmentskillssocialsocial rolesynapsetransmission processwomen compared to menwomen compared with menwomen versus menwomen vs. men

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Description preview

Project Abstract
The ability to efficiently defend one’s home territory from intruders is an essential behavioral adaptation.

However, the neurobiology of this experience-dependent plasticity is unknown. Furthermore, the neural

mechanisms in females and sex differences are also unknown; these are critical barriers of therapeutic

interventions…

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Synaptic plasticity underlying sex differences in aggression reward — UNIVERSITY OF MINNESOTA | UNITED STATES | Dec 2023 | Dev Procure