grant
Suicide Circuit Therapeutics: Engaging Novel Targets with Rapid and Individualized MRI-Guided Accelerated TMS
Organization MASSACHUSETTS GENERAL HOSPITALLocation BOSTON, UNITED STATESPosted 1 May 2023Deadline 31 Mar 2029
NIHUS FederalResearch GrantFY2026AccelerationAcuteAddressAnteriorAreaBiologicalBiological MarkersBrainBrain Nervous SystemCause of DeathCell PhoneCellular PhoneCellular TelephoneClinicalDevelopmentDevicesDigital biomarkerDysfunctionEmotional DepressionEncephalonFamilyFeeling suicidalFunctional disorderFutureHospital AdmissionHospitalizationIncidenceIndividualInferiorInvestmentsLobuleMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMeasuresMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMental DepressionMental Health ServicesMental Hygiene ServicesMobile PhonesModelingNMR ImagingNMR TomographyNuclear Magnetic Resonance ImagingParietalPatientsPhasePhysiologic pulsePhysiopathologyPositionPositioning AttributePrefrontal CortexProtocolProtocols documentationPsychiatric therapeutic procedurePsychiatryPulseRandomizedResearchResearch ResourcesResourcesSafetySuicidal thoughtsSuicideSuicide attemptSuicide precautionSuicide preventionTherapeuticTranscranial magnetic stimulationTreatment EfficacyZeugmatographyanti-depressant agentanti-depressant drugsanti-depressantsanti-depressive agentsbehavior measurementbehavioral measurebehavioral measurementbio-markersbiologicbiologic markerbiomarkercingulate cortexclinical efficacycommit suicidecompleted suicideconfirmatory efficacy trialconfirmatory trialdepressiondepression symptomdepressivedepressive symptomsdevelopmentaldigital markereffective therapyeffective treatmentelectric fieldexecutive controlexecutive functionfatal attemptfatal suicideiPhoneinnovateinnovationinnovativeinpatient psychiatric careinpatient psychiatric treatmentintent to dieintervention efficacymental health careneural controlneural regulationneuromodulationneuromodulatoryneuroregulationnew markernon fatal attemptnonfatal attemptnovelnovel biomarkernovel markerpathophysiologypredictive biological markerpredictive biomarkerspredictive markerpredictive molecular biomarkerprevent suicidalityprevent suicidepsychiatric carepsychiatric hospitalizationpsychiatric therapypsychiatric treatmentrandomisationrandomizationrandomly assignedreduce suicidalityreduce suicidereducing suicidalityreducing suicideresponseresponse biomarkerresponse markerssmart phonesmartphonesuicidalsuicidal attemptsuicidal behaviorsuicidal ideationsuicidal patientsuicidal thinkingsuicidalitysuicidality preventionsuicide behaviorsuicide ideationsuicide interventionsuicide patientsuicide ratesuicidestherapeutic efficacytherapy efficacythoughts about suicidetreatment strategywearablewearable devicewearable electronicswearable systemwearable technologywearable toolwearables
Description preview
PROJECT SUMMARY AND ABSTRACT
Suicide is a leading cause of death worldwide, with tragic consequences for individuals and their families.
Despite the increased access to mental health services and use of psychiatric treatments, suicide rates have
remained unchanged over the last century. Worse, from 1999 to 2019 suicide rates increased 33% in the…
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