grant
Subjective and Somatic Tinnitus; Using Functional Near-Infrared-Spectroscopy to Identify Objective Correlates in Auditory and Non-Auditory Cortices
Organization UNIVERSITY OF PITTSBURGH AT PITTSBURGHLocation PITTSBURGH, UNITED STATESPosted 9 Sept 2024Deadline 31 Aug 2029
NIHUS FederalResearch GrantFY2025Accuracy of DiagnosisAgeAlgorithmsAnimal ModelAnimal Models and Related StudiesAnimalsAuditoryAuditory CortexAuditory PerceptionAuditory areaBrainBrain Nervous SystemBrain StemBrain imagingBrainstemCausalityClinicalClinical TreatmentCoupledDataDevicesDiagnosticDiseaseDisorderEar CanalEncephalonEngineeringEtiologyExhibitsExternal Acoustic MeatusExternal auditory canalFundingGoalsGrantHead and NeckHead and neck structureHearing LossHemoglobinHumanHypoacusesHypoacusisKnowledgeLightLoudnessMachine LearningMaintenanceMapsMeasurableMeasuresModern ManMovementParticipantPathologyPatientsPatternPerceptionPhotoradiationPrevalencePropertyPublishingQuestionnairesReportingResearchRestRinging-Buzzing-TinnitusScalpScalp structureSensitivity and SpecificitySeveritiesStandardizationSubjective TinnitusTinnitusTransmissionTrigeminal SystemVariantVariationVisualabsorptionagesanalogauditory pathwaybody movementbrain visualizationcausationclinical interventionclinical therapycomputer based predictiondesigndesigningdiagnostic accuracydisease causationdysfunctional hearingfNIRSfunctional near infrared spectroscopyhearing challengedhearing defecthearing deficienthearing deficithearing difficultyhearing dysfunctionhearing impairmenthearing perceptionhemodynamicshuman subjectindexinginnovateinnovationinnovativejaw movementmachine based learningmachine learned algorithmmachine learning algorithmmachine learning based algorithmmodel of animalneuralneural correlatepersonalization of treatmentpersonalized medicinepersonalized therapypersonalized treatmentprediction algorithmpredictive modelingprognosticresponsesomatosensorysoundsound perceptiontinnitus auriumtooltransmission processtrial regimentrial treatmenttrigeminal
Description preview
Abstract: Phantom sound perception (tinnitus) arises from aberrant central auditory pathways. Subjective
tinnitus is typically caused by hearing loss. Auditory cortex (AC) in tinnitus animal models exhibits increased
spontaneous neural firing and synchrony. Another subset of tinnitus exists whereby patients (80%) can
manipulate pitch, tone and/or…
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