grant
Study cell cycle regulation in dormant tumor cells
Organization DIVISION OF BASIC SCIENCES - NCILocation UNITED STATES
NIHUS FederalResearch GrantFY2025BiosensorCell BodyCell CycleCell Cycle ControlCell Cycle RegulationCell Division CycleCell Growth in NumberCell MultiplicationCell ProliferationCellsCellular ProliferationDecision MakingFutureGoalsImageMalignant CellMolecularProliferatingRegulationTumor Cellanaphase-promoting complexbiological sensorcancer cellcell typecyclosomeenzyme activityimaginginterestneoplastic cellnew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeuticsnew therapynext generation therapeuticsnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeuticsnovel therapysenescencesenescenttumor growth
Description preview
Cells can exit the cell cycle into a number of different states. Temporary cell cycle exit is referred to as quiescence, while more permanent, irreversible cell cycle exit is referred to as senescence. How and why cells choose between these different types of cell cycle exit is not completely known. Understanding the molecular mechanisms that…
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