grant
Structure and mechanism of the polar tube invasion apparatus from microsporidian parasites
Organization JOHNS HOPKINS UNIVERSITYLocation BALTIMORE, UNITED STATESPosted 1 Aug 2025Deadline 31 Jul 2030
NIHUS FederalResearch GrantFY2025AIDSAcquired Immune DeficiencyAcquired Immune Deficiency SyndromeAcquired Immunodeficiency SyndromeActinsAddressAnimalsArchitectureAreaAssayBioassayBiochemicalBiochemistryBiological AssayBiological ChemistryBiologyBiophysicsCategoriesCell BodyCellsCellular MatrixClassificationComplexCryo-electron MicroscopyCryo-electron tomographyCryoelectron MicroscopyCytoplasmCytoskeletal SystemCytoskeletonDataDiseaseDisorderE intestinalisE. intestinalisElectron CryomicroscopyEncephalitozoon (Septata) intestinalisEncephalitozoon intestinalisEngineering / ArchitectureEventFilamentFire - disastersFiresHumanImmunocompromisedImmunocompromised HostImmunocompromised PatientImmunosuppressed HostIn SituIn VitroIndividualInfectionInjectionsInsectaInsectsInsects InvertebratesInvadedMediatingMembraneMicroscopyMicrosporaMicrospora InfectionsMicrosporeaMicrosporidaMicrosporidiaMicrosporidiosisModelingModern ManModernizationMolecularMolecular ConfigurationMolecular ConformationMolecular StereochemistryMonitorMsecNIAIDNational Institute of Allergy and Infectious DiseaseOpticsOrganellesParasitesPatientsPhagocytosisProcessProteinsReproduction sporesResolutionS intestinalisS. intestinalisSeptata intestinalisSequence HomologySingle Crystal DiffractionSporesStructureSurfaceSystematicsTechniquesTimeTubeWorkX Ray CrystallographiesX-Ray CrystallographyX-Ray Diffraction CrystallographyX-Ray/Neutron CrystallographyXray Crystallographybiodefensebiophysical foundationbiophysical principlesbiophysical sciencesburden of diseaseburden of illnessconformationconformationalconformational stateconformationallyconformationscryo-EMcryo-EM tomographycryoEMcryoEM tomographycryoelectron tomographycryogenic electron microscopydisease burdenelectron cryo-tomographyelectron tomographyemerging pathogenexperimentexperimental researchexperimental studyexperimentsextracellularfirehuman pathogenimmunosuppressed patientin vivoinsightintracellular skeletonlight microscopymembrane structuremillisecondnew pathogennovel pathogenopportunistic pathogenopticalparticlepriority pathogenprotein complexprotein protein interactionprotein purificationresolutionsstructural biologytime usetool
Description preview
Project Summary/Abstract
Microsporidia are unicellular, fungal parasites with a wide host-range, from insects to humans. They are
emerging pathogens, classified as NIAID Category B opportunistic pathogens, and cause microsporidiosis in
immunocompromised patients. To gain entry into a target cell, microsporidia employ a remarkably unique and…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click