grant
Striatal Mu Opioid Receptor Containing Neurons in L-DOPA induced dyskinesia
Organization UNIVERSITY OF FLORIDALocation GAINESVILLE, UNITED STATESPosted 4 May 2026Deadline 30 Apr 2028
NIHUS FederalResearch GrantFY20266-OHDA6-hydroxydopamineAI systemAdvisory CommitteesAffectAmalgamArtificial IntelligenceBehaviorBehavioralCalciumCell Communication and SignalingCell SignalingChronicCommunitiesComputer ReasoningCorpus StriatumCorpus striatum structureData AnalysesData AnalysisDevelopmentDoctor of PhilosophyDorsalDyskinesia SyndromesDystoniaElectrophysiologyElectrophysiology (science)EligibilityEligibility DeterminationEventFiberFloridaGeneticGoalsHumanHyperkinesiaHyperkinesisHyperkinetic MovementsImageIn vivo two-photon calcium imagingInjectionsIntracellular Communication and SignalingInvestigatorsInvoluntary MovementsKnowledgeL-DOPA induced dyskinesiaL-DopaLateralLearningLesionLevodopaLevodopa dyskinesiaLinkLong-Term PotentiationMachine IntelligenceMachine LearningMediationMedicalMentorsMethodsMiceMice MammalsModelingModern ManMonitorMovement Disorder SyndromesMovement DisordersMurineMusMuscle DystoniaMuscle SpasmMuscular SpasmNegotiatingNegotiationNerve CellsNerve DegenerationNerve UnitNeural CellNeurocyteNeuron DegenerationNeuronsNeuropharmacologyNeurophysiology - biologic functionNeurophysiology / ElectrophysiologyNeurosciencesOpiate ReceptorsOpiatesOpioidOpioid ReceptorOpticsOutputOxidopamineParalysis AgitansParkinsonParkinson DiseasePathway interactionsPatientsPh.D.PhDPharmacologyPhasePhotometryPhotonsPhysiologicPhysiologicalPopulationPosturePredispositionPrimary ParkinsonismProtocol ScreeningPublicationsReceptor GeneReceptor ProteinResearchResearch PersonnelResearchersRoleRunningScientific PublicationSeveritiesSignal TransductionSignal Transduction SystemsSignalingSingle Base PolymorphismSingle Nucleotide PolymorphismSpasmStriate BodyStriatumSubgroupSusceptibilitySymptomsSystemTask ForcesTechniquesTestingTrainingUniversitiesVariantVariationabnormal involuntary movementadvisory teambiological signal transductioncalcium indicatorcomputational neurosciencedata interpretationdesigndesigningdevelopmentalelectrophysiologicalexperiencegenetic approachgenetic strategyimagingin vivo calcium imaginginnovateinnovationinnovativelarge data setslarge datasetslearning activitylearning methodlearning strategieslearning strategylevodopa induced dyskinesiamachine based learningmachine learning based methodmachine learning methodmachine learning methodologiesmeetingmeetingsmotor symptommu opioid receptorsmultidisciplinaryneuralneural degenerationneural functionneurodegenerationneurodegenerativeneurological degenerationneuronalneuronal degenerationnew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeuticsnew therapynext generation therapeuticsnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeuticsnovel therapyopticalpatch clamppathwayreceptorsingle nucleotide variantskillssocial rolestriataltraittranslation strategytranslational approachtranslational strategyμ opioid receptorsμ-ORμOR
Description preview
Project Summary/Abstract:
Candidate: My goal is to become an independent investigator running a multidisciplinary, translational, systems
neuroscience lab which investigates mechanisms underlying specific symptoms of movement disorders and
designs translational strategies. My lab will use electrophysiology and optical neuroscience techniques…
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