grant

Stand & Move at Work II: Effectiveness and Implementation

Organization ARIZONA STATE UNIVERSITY-TEMPE CAMPUSLocation SCOTTSDALE, UNITED STATESPosted 10 Aug 2020Deadline 31 Jul 2026
NIHUS FederalResearch GrantFY202421+ years oldActive Follow-upAddressAdherenceAdultAdult HumanAdult-Onset Diabetes MellitusBehavior Conditioning TherapyBehavior ModificationBehavior TherapyBehavior TreatmentBehavioralBehavioral Conditioning TherapyBehavioral ModificationBehavioral TherapyBehavioral TreatmentBindingBody WeightCancersCardiovascular DiseasesChronic DiseaseChronic IllnessCompetenceConditioning TherapyCosts and BenefitsDimensionsEffectivenessEmployeeEvidence based interventionGovernmentHealthHealth BenefitHealth PromotionHealth ServicesIndustryInternetInterventionIntervention StrategiesInterviewInvestmentsJob LocationJob PlaceJob SettingJob SiteJobsKetosis-Resistant Diabetes MellitusKnowledgeMaintenanceMalignant NeoplasmsMalignant TumorManufacturerMaturity-Onset Diabetes MellitusMeasuresMolecular InteractionMusculoskeletal PainNIDDMNon-Insulin Dependent DiabetesNon-Insulin-Dependent Diabetes MellitusNon-Profit OrganizationsNoninsulin Dependent DiabetesNoninsulin Dependent Diabetes MellitusNonprofit OrganizationsOccupationsPARiHS frameworkProfessional PositionsPromoting Action on Research Implementation in Health Services frameworkPublic HealthQOLQuality of lifeRandomization trialRandomizedReportingResearchRiskRisk FactorsRoleSalutogenesisSedentary behaviorSedentary life-styleSlow-Onset Diabetes MellitusSocietiesSpeedStable Diabetes MellitusT2 DMT2DT2DMTestingTimeTranslatingType 2 Diabetes MellitusType 2 diabetesType II Diabetes MellitusType II diabetesVariantVariationVendorWWWWorkWork LocationWork PlaceWork-SiteWorkplaceWorksiteactive followupadult onset diabetesadulthoodarmassess effectivenessbehavior interventionbehavioral interventioncardiovascular disorderchronic disordercostdetermine effectivenesseffectiveness assessmenteffectiveness evaluationeffectiveness testingeffectiveness trialeffectiveness/implementation hybridefficacy trialergonomicsevaluate effectivenessexamine effectivenessflexibilityflexiblefollow upfollow-upfollowed upfollowupimplementation costimplementation facilitationimplementation fidelityimplementation investmentimplementation outcomesimplementation questionsimplementation strategyimplementation trialimplementation/effectivenessimprovedincremental costinnovateinnovationinnovativeintervention armintervention costintervention designintervention effectintervention programinterventional strategyketosis resistant diabetesmalignancymaturity onset diabetesmortalityneoplasm/cancerpost implementationpreservationpreventpreventingprimary outcomeprogramspromoting healthpublic health interventionpublic health prioritiesquestions about implementationrandomisationrandomizationrandomized trialrandomly assignedsedentarysedentary lifestylesocialsocial rolestrategies for implementationtherapy designtreatment armtreatment designtrendtrial designtype 2 DMtype II DMtype two diabeteswebwork settingwork-studyworld wide web
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Full Description

Project Summary
Sedentary behavior (i.e., sitting) has emerged as an important risk factor for type 2 diabetes, cardiovascular

disease, some cancers, and mortality. Working adults with desk-bound occupations accumulate large volumes

of daily sedentary time. Sit-stand workstations are now the fastest growing employee benefit, yet evidence-based

interventions are not being implemented to support their use. Our team has completed the largest and most

definitive efficacy trial on the impact of an intervention to support use of sit-stand workstations and reduce

sedentary behavior in the workplace. Stand & Move at Work (SMW) is a multicomponent, social-ecological

behavioral intervention tested in 24 industry, government, and academic worksites (N=630 workers). Intervention

effects included: (a) reductions in sedentary time at 12 months (~60 min/8 h workday) that were retained at 24-

month follow-up (~30 min/8 h workday); (b) reduced body weight and improved chronic disease risk factors

among those with high baseline risk; and (c) reduced musculoskeletal pain. We are now proposing a new trial

that tests the role of expert-based facilitation to enhance effectiveness and implementation of the SMW

intervention. We use the Integrated - Promoting Action on Research Implementation in Health Services

(iPARIHS) framework to inform our new trial through: (a) organizing our implementation outcomes from our

efficacy trial; (b) conducting industry-based discovery interviews; and (c) piloting our enhanced implementation

strategy in new worksites. We propose a 2-arm group-randomized hybrid effectiveness-implementation (type 2)

trial to test the effectiveness of SMW for reducing sedentary time in the workplace, and to test an implementation

strategy (i.e., expert facilitation) for improving implementation fidelity. Worksites (N=24) will be observed over 3

months of sit-stand workstation use only, and will then be randomized to 12 months of either: (a) SMW (web-

delivered); or (b) SMW+ (web-delivered + expert facilitation). Our dual primary outcomes will be reductions in

objectively-measured sedentary time (effectiveness) and intervention fidelity (implementation) over 12 months.

Because facilitation increases intervention cost, we will also assess incremental cost benefit of our interventions

(secondary aim). Finally, we will explore fidelity as a driver of effectiveness, examine within-worksite differences

in sedentary time pre- and post- implementation, and measure organizational sustainability of effectiveness and

implementation at 24 months. The potential health benefits of sit-stand workstations and associated worksite

health promotion programs will not be realized in the workforce at large until we test the most effective and

efficient way to implement evidence-based interventions. This project is among the first initiatives to address this

growing trend in worksite health, and will answer important questions related to effectiveness, implementation,

and cost benefit. Optimal strategies for delivering the SMW intervention will be identified and new knowledge will

be generated on how facilitation can enhance implementation fidelity of workplace health initiatives, both of which

will increase the public health impact of evidence-based interventions.

Grant Number: 5R01CA250527-05
NIH Institute/Center: NIH

Principal Investigator: Matthew Buman

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