grant
Simultaneous Downfield and Upfield proton MRSI at 3T
Organization JOHNS HOPKINS UNIVERSITYLocation BALTIMORE, UNITED STATESPosted 1 Sept 2024Deadline 30 Jun 2028
NIHUS FederalResearch GrantFY20251H- Nuclear Magnetic Resonance Spectroscopic Imaging3-D3-Dimensional3DAccelerationBindingBrainBrain Nervous SystemBrain imagingCell Communication and SignalingCell SignalingChemicalsClinicalCommunitiesComputer softwareDataDevelopmentDiseaseDisorderEncephalonFrequenciesFutureGoalsH+ elementHumanHydrogen IonsHydrogen OxideImageImaging ProceduresImaging TechnicsImaging TechniquesIntracellular Communication and SignalingMR ImagingMR SpectroscopyMR TomographyMRIMRIsMRSIMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMapsMeasurementMeasuresMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMetabolicMethodologyMethodsModern ManMolecular InteractionNMR ImagingNMR TomographyNervous System DiseasesNervous System DisorderNeurologic DisordersNeurological DisordersNeurosciencesNuclear Magnetic Resonance ImagingOncologyOncology CancerPhasePhysiologicPhysiologic pulsePhysiologicalProton Magnetic Resonance Spectroscopic ImagingProtonsPulseRelaxationReproducibilityResearchResearch ProposalsResolutionRunningScanningSideSignal TransductionSignal Transduction SystemsSignalingSliceSoftwareSurvey InstrumentSurveysSystemTechniquesTemperatureTimeUncertaintyVisualizationWaterZeugmatographybiological signal transductionbrain metabolismbrain visualizationclinical applicabilityclinical applicationdata acquisitiondata acquisitionsdevelopmentaldoubtexperimentexperimental researchexperimental studyexperimentshealthy volunteerhuman imagingimagingimaging spectroscopyimaging studyimprovedin vivomagnetic resonance spectroscopic imagingmetabolic imagingneural imagingneuro-imagingneuroimagingneurological diseaseneurological imagingnew approachesnovelnovel approachesnovel strategiesnovel strategyopen sourcereconstructionresolutionsspectroscopic imagingthree dimensionaltime usetool
Description preview
PROJECT SUMMARY
In the past, nearly all clinical and research proton magnetic resonance spectroscopy (MRS) studies of
human brain metabolism have focused on the resonances upfield (UF) from the water signal. However, over
the last few years it has been demonstrated that there are signals downfield (DF) from water that can be
visualized using…
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