grant
Sensory-motor transformations in a neural circuit for object-directed walking
Organization MAX PLANCK FLORIDA CORPORATIONLocation Jupiter, UNITED STATESPosted 20 May 2026Deadline 30 Apr 2031
NIHUS FederalResearch GrantFY20262-photon3-D3-Dimensional3DAccelerationAddressAnatomic SitesAnatomic structuresAnatomyAnimalsArthropodaArthropodsAutomobile DrivingBehavior ControlBehavioralBehavioral ManipulationBilateralBiologic ModelsBiological ModelsBiophysicsBody SizeBrainBrain HemisphereBrain Nervous SystemBrain StemBrainstemCalibrationCell BodyCellsCementationCerebral hemisphereConnector NeuronContralateralDataDiseaseDisorderDrosophilaDrosophila genusDrosophila melanogasterElectrophysiologyElectrophysiology (science)EncephalonEnvironmentEventFeedbackFliesFootballGoalsHistoryHolographyHumanIntercalary NeuronIntercalated NeuronsInterneuronsInternuncial CellInternuncial NeuronInvertebrataInvertebratesIpsilateralJointsKnowledgeLegLiteratureMammaliaMammalsManufactured footballMapsMeasuresMedulla SpinalisModel SystemModelingModern ManMolecular ConfigurationMolecular ConformationMolecular StereochemistryMorphologyMotorMotor outputMovementNeckNerveNerve CellsNerve UnitNeural CellNeurocyteNeuronsNeurophysiology / ElectrophysiologyOutputPartner in relationshipPathway interactionsPatternPeripheralPhysiologyPopulationPopulation HeterogeneityRecording of previous eventsResolutionSensoryShapesSpinal CordSynapsesSynapticSystemTechniquesTestingUpdateVertebrate AnimalsVertebratesVisualVisual FieldsVisual PathwaysWalkingWhole-Cell RecordingsWorkWritinganalogbehavioral controlbiophysical foundationbiophysical principlesbiophysical sciencesbody movementbrain controlbrain pathwayconformationconformationalconformational stateconformationallyconformationsconnectomedesigndesigningdetectordiverse populationsdrivingelectrophysiologicalexperimentexperimental researchexperimental studyexperimentseye fieldeye trackingflexibilityflexibleflyfruit flyheterogeneous populationhigh definitionhigh-resolutionhistoriesin vivoinsightkinematic modelkinematicsmatemotor controlnetwork modelsneuralneural circuitneural circuitryneurocircuitryneuronalnoveloptogeneticspathwayperceptual stimulusphysicochemical phenomena related to the sensespopulation diversityreceptive fieldrecruitresolutionssensory inputsensory stimulussynapsesynaptic circuitsynaptic circuitrythree dimensionaltwo-photonvertebratavirtualvisual stimulusvisual trackingwalking pacewalking speed
Description preview
Walking towards a salient object (prey, mate, etc.) is a basic and conserved behavioral motif shared across
most terrestrial animals, including humans. Mobility disorders often impact this vital function of goal-directed
walking. Despite varied evolutionary histories, both vertebrates and invertebrates have converged on similar leg-
kinematics…
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