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Secondary Histologic Analysis of TUS Studies

Organization STANFORD UNIVERSITYLocation STANFORD, UNITED STATESPosted 1 Jan 2024Deadline 31 Dec 2025 ⚠️
NIHUS FederalResearch GrantFY2025AcousticsAddictive BehaviorAffectAnimal ModelAnimal Models and Related StudiesAssayAstrocytesAstrocytusAstrogliaBioassayBiological AssayBody TissuesBrainBrain Nervous SystemCell BodyCellsCephalicClinical TrialsCranialDataDiagnostic ImagingDiseaseDisorderDoseEchographyEchotomographyEncephalonEpilepsyEpileptic SeizuresEpilepticsGliaGlial CellsHistologicHistologicallyHistologyHortega cellHumanIRBIRBsImageImmuneImmunesImmunohistochemistryImmunohistochemistry Cell/TissueImmunohistochemistry Staining MethodIn Situ Nick-End LabelingInflammatoryInflammatory ResponseInstitutional Review BoardsInvestigationInvestigatorsKolliker's reticulumLateral Geniculate BodyLocationManuscriptsMedical UltrasoundMental DepressionMental HealthMental HygieneMetabolicMethodsMicrogliaModern ManMolecularMorphologyNerve CellsNerve UnitNeural CellNeurocyteNeurogliaNeuroglial CellsNeurologicNeurologicalNeuronsNon-neuronal cellNonneuronal cellNucleus AccumbensOutcomeOvineOvisPainPainfulPersonsPhysiologic pulsePopulationPsychological HealthPublishingPulseQualifyingRadiationReactionReportingResearchResearch PersonnelResearchersResolutionSafetySeizure DisorderSheepSonicationSourceSpottingsStaining methodStainsStressSubstance Use DisorderSubstance abuse problemTUNELTimeTissuesTitrationsUltrasonic ImagingUltrasonogramUltrasonographyUltrasound DiagnosisUltrasound Medical ImagingUltrasound TestVisual Evoked PotentialsVisual Evoked ResponseVisual evoked cortical potentialVisualizationWorkabuse of substancesagedastrocytic gliabehavior studybehavioral studybrain cellcell typecomputer imagingcytokinedata sharingdepressiondiagnostic ultrasounddigital imagingepilepsiaepileptogenicexperiencegitter cellhistologic studieshistological studiesimagingimaging studylateral geniculatelateral geniculate nucleusmesogliamicroglial cellmicrogliocytemodel of animalnerve cementneural controlneural regulationneuromodulationneuromodulatoryneuronalneuroregulationnon-invasive brain stimulationperivascular glial cellpressureresolutionsresponsesecondary analysissonogramsonographysound measurementsubstance abusesubstance use and disordersubstance use treatmentterminal nick end labelingtoolultrasoundultrasound imagingultrasound scanning

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Description preview

Project Abstract
The nucleus accumbens (NAc) is a target for non-invasive brain stimulation for the treatment of substance use
disorders (SUDs). Due to its location deep in the brain, transcranial ultrasound stimulation (TUS) is unique
among non-invasive brain stimulation methods to be able to focus on the NAc with high spatial resolution.
TUS has…

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