grant

San Francisco Bay Clinical Trials Unit (CTU)

Organization PUBLIC HEALTH FOUNDATION ENTERPRISESLocation CITY OF INDUSTRY, UNITED STATESPosted 2 Mar 2007Deadline 30 Nov 2027
NIHUS FederalResearch GrantFY2026AACTGACTGAIDS VaccinesAIDS VirusAIDS clinical trial groupAIDS focused researchAIDS preventionAIDS related researchAIDS researchAIDS scienceAIDS specific researchAIDS vaccineAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAdherenceAffectAnti-Retroviral AgentsAntibodiesAreaAutomobile DrivingBehavioral SciencesCaringClinical TrialsClinical Trials NetworkClinical Trials UnitCommunicationCommunitiesDevelopmentDisease remissionDrug userEnrollmentEnsureEpidemicEpidemiologyGenerationsGoalsGrantGroomingHBV cureHBV functional cureHIVHIV InfectionsHIV PreventionHIV Vaccine Trials NetworkHIV cureHIV diagnosisHIV focused researchHIV functional cureHIV individualsHIV infected individualsHIV infected personsHIV interventionHIV investigationHIV peopleHIV positive individualsHIV positive peopleHIV related researchHIV researchHIV scienceHIV specific researchHIV therapeuticHIV therapyHIV treatmentHIV vaccineHIV viral infectionHIV virus infectionHIV-1 cureHIV-1 functional cureHIV-1 infectionHIV-1 interventionHIV-1 preventionHIV-1 therapeuticHIV-1 therapyHIV-1 treatmentHIV/AIDS VaccinesHIV/AIDS cureHIV/AIDS preventionHVTNHepatitisHomeHuman Immunodeficiency Virus therapyHuman Immunodeficiency Virus treatmentHuman Immunodeficiency VirusesInfectionInfection by HIV-1Infection from HIV-1Infection of HIV-1InflammationInfrastructureInjectableInjecting drug userInjection Drug UserInvestigation on HIVInvestigatorsJournalsLAV-HTLV-IIILeadershipLocationLymphadenopathy-Associated VirusM tuberculosis infectionM. tb infectionM. tuberculosis infectionM.tb infectionM.tuberculosis infectionMSMMTB infectionMagazineMan who have sex with ManManuscriptsMentorshipMultipurpose prevention technologyMycobacterium tuberculosis (MTB) infectionMycobacterium tuberculosis infectionOutputPLWHPWHPWIDPWUDPhasePopulationPositionPositioning AttributePrEPPrevent HIVPreventative strategyPreventionPrevention ProtocolsPrevention strategyPrevention trialPreventive strategyProcessProtocolProtocols documentationPublicationsRecordsRemissionResearchResearch InfrastructureResearch PersonnelResearchersRiskRoleRunningSan FranciscoScienceScientific PublicationScientistSiteStructureTB infectionTB therapyTB treatmentTalentsTextilesTrainingTransportationTreatment ProtocolsTreatment RegimenTreatment ScheduleTuberculosisVaccine ResearchVaccinesVaginal RingViralVirus-HIVWorkacquired immunodeficiency syndrome clinical trial groupanti-retroviralbehavioral and social scienceclinical research siteclinical sitecommunity engagementdata qualitydesigndesigningdevelopmentaldisparities in racedisparity due to racedisparity in ethnicdisseminated TBdisseminated tuberculosisdrivingefficacy trialengagement with communitiesenrollepidemiologicepidemiologicalethnic based disparityethnic disadvantageethnic disparityethnic inequalityethnic inequityethnic minorityethnicity disparityexperiencefabrichepatitis B curehepatitis B functional curehepatitis B virus curehepatitis B virus functional curehomeshuman immunodeficiency virus curehuman immunodeficiency virus infectionhuman immunodeficiency virus researchhuman immunodeficiency virus vaccineimprovedindividuals infected with HIVindividuals with HIVindividuals with human immunodeficiency virusinequality due to raceinequity due to raceinfected with HIVinfected with human immunodeficiency virusinfection due to Mycobacterium tuberculosisintravaginal ringmen having sex with menmen who have sex with menmen who have sex with other menmultipurpose preventionneutralizing antibodypeople infected with HIVpeople infected with human immunodeficiency viruspeople living with HIVpeople who inject drugspeople who inject illicit drugspeople who use drugspeople who use illicit drugspeople with HIVpeople with human immunodeficiency viruspersons who inject drugspersons who use drugspre-exposure prophylaxisprevent AIDSprevent human immunodeficiency virusprogramsrace based disparityrace based inequalityrace based inequityrace disparityrace related disparityrace related inequalityrace related inequityracial disparityracial inequalityracial inequityracial minorityracially unequalrecruitresearch addressing HIVresearch in HIVresearch into HIVresearch on HIVresearch on human immunodeficiency virusresearch to address HIVscience on HIVscience to address HIVsocial rolesocial science researchstudies on HIVtraining opportunitytreat HIVtreat Human Immunodeficiency Virustreat M. tuberculosistreat Mtbtreat Mycobacterium tuberculosistreat tbtreat tuberculosistreatment trialtuberculosis infectiontuberculosis therapytuberculosis treatmenttuberculous spondyloarthropathyvaccination studyvaccination trialvaccine against HIVvaccine studyvaccine trialvaccine-related researchwork groupworking group
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Full Description

The San Francisco Bay Area has experienced a particularly intense HIV epidemic, with men who have sex with men (MSM) most heavily impacted in the region; and people who inject drugs important populations for engagement. Drs. Susan Buchbinder and Diane Havlir are scientific leaders in HIV prevention and treatment, respectively. Together they will lead the San Francisco Bay Area Clinical Trials Unit (SFBay CTU), affiliated with the ACTG, HPTN, and HVTN.

This integrated research organization will accomplish 3 specific aims through these Networks: 1) advance prevention and treatment science and their intersection within the Clinical Trials Networks; 2) implement clinical trials efficiently and with excellent adherence to protocol while engaging communities; and 3) develop a new generation of leaders in HIV prevention and treatment science. Drs. Buchbinder and Havlir are joined by a pool of talented investigators who have provided leadership across the Networks, serving on numerous scientific leadership committees and working groups and chairing a range of prevention and treatment protocols. The two Clinical Research Sites, the Bridge HIV CRS (affiliated with HVTN and HPTN and led by Dr.

Hyman Scott) and the UCSF CRS (affiliated with ACTG and led by Dr. Annie Leutkemeyer) have records of excellence in enrollment, retention, and adherence to protocol requirements, and actively engage local communities throughout the San Francisco Bay Area. This application represents a renewal of the SFBay CTU, with several improvements, including new leadership by an accomplished group of investigators; integration of community programs into a single, status-neutral team; expansion of community engagement and recruitment into the East and South Bays of San Francisco; and full integration of early stage investigators in all aspects of the science of the SFBay CTU. Through a smoothly running research infrastructure, divided into Scientific, Operational, and Community Engagement Steering Committees, the SFBay CTU is committed to continued leadership in the ACTG, HPTN, and HVTN, and contributing to breakthroughs in the science of HIV prevention, treatment, and cure.

Grant Number: 5UM1AI069496-20
NIH Institute/Center: NIH

Principal Investigator: Susan Buchbinder

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San Francisco Bay Clinical Trials Unit (CTU) — PUBLIC HEALTH FOUNDATION ENTERPRISES | UNITED STATES | Mar 2007 | Dev Procure