grant
Role of the parasubthalamic nucleus (PSTN) in the central regulation of feeding behavior
Organization WILLIAMS COLLEGELocation WILLIAMSTOWN, UNITED STATESPosted 16 Apr 2025Deadline 31 Mar 2028
NIHUS FederalResearch GrantFY2025ACTH-Releasing FactorAffectAppetiteAppetite RegulationAppetite StimulantsAppetite-Stimulating DrugsAttenuatedBehaviorBody WeightBody Weight decreasedBrainBrain Nervous SystemCCKCRF-41CachecticCachexiaCancersCell NucleusCholecystokininClinicalCorticoliberinCorticotropin-Releasing FactorCorticotropin-Releasing Factor-41Corticotropin-Releasing HormoneCorticotropin-Releasing Hormone-41Desire for foodDetectionDiseaseDisorderDistressEatingEncephalonEndocrine Gland SecretionEquilibriumFeeding behaviorsFiberFoodFood IntakeFood Intake RegulationGLP-1GeneticGlp-1HealthHistologicHistologicallyHormonesHungerHypothalamic structureHypothalamusIndividualInfectionIngestive BehaviorInsulinoma amyloid peptideInvestigationL-tyrosyl-L-tyrosineLateralLearningLeptinMajor Depressive DisorderMalignant NeoplasmsMalignant TumorMalnutritionMapsMediatingMiceMice MammalsMotivationMurineMusNerve CellsNerve UnitNeural CellNeurocyteNeuronsNucleusNutritional DeficiencyOb Gene ProductOb ProteinObese Gene ProductObese ProteinOver weightOverweightPYY PeptidePancreozyminPatternPeptide YYPhotometryPlayPopulationPosterior Hypothalamic RegionPosterior HypothalamusRegulationResearchRoleScientistSourceStimulusStomachSystemTachykininTechniquesTestingTherapeutic HormoneTrainingTyr-TyrUndernutritionUnited StatesUropancreozyminWeight LossWeight Reductionamlintideamylinappetite lossattenuateattenuatesbalancebalance functionbody weight losscareercell typeclinical depressioncollegecollegiatecorticotropin releasing hormonediabetes associated peptidedietary deficiencyeconomic costexperimentexperimental researchexperimental studyexperimentsfeeding-related behaviorsfood Ingestionfood consumptiongastricgastrointestinalghrelinglucagon-like peptide 1hypothalamicinsightinsulinoma amyloid polypeptideinterestislet amyloid polypeptidemajor depressionmajor depression disordermalignancymalnourishedneoplasm/cancerneuralneuronalnew drug targetnew druggable targetnew pharmacotherapy targetnew therapeutic targetnew therapy targetnext generationnovel drug targetnovel druggable targetnovel pharmacotherapy targetnovel therapeutic targetnovel therapy targetnutrient intake activitynutrition deficiencynutrition deficiency disordernutritional deficiency disorderold ageorexigenicpancreatic amylinpeptide tyrosine-tyrosineresponsesocial roletooltyrosyltyrosineundergradundergraduateundergraduate research experienceundergraduate research opportunitiesundergraduate research programsundergraduate studentwt-loss
Description preview
PROJECT SUMMARY
The motivation to eat depends on the relative balance of activity between orexigenic (appetite inducing)
and anorexigenic (appetite suppressing) brain systems. An abnormal balance of activity in these
systems can lead to substantial health problems with high associated economic costs. In the United
States, over half the population…
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