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Role of the circadian rhythm on endocannabinoid response to an acute stress
Organization OREGON HEALTH & SCIENCE UNIVERSITYLocation PORTLAND, UNITED STATESPosted 1 Jan 2021Deadline 31 Dec 2025 ⚠️
NIHUS FederalResearch GrantFY202521+ years oldAcuteAdultAdult HumanAeroseb-HCAffectAgeAnalgesic ManagementApoplexyAreaArithmeticArousalAttenuatedBehaviorBiologicalBlackBlack AmericanBlack PopulationsBlack groupBlack individualBlack peopleBlack raceBlacksBlood PlasmaBlood PlateletsBrain Vascular AccidentCardiacCardiac ChronotropismCardiac DiseasesCardiac DisordersCardiovascularCardiovascular Body SystemCardiovascular DiseasesCardiovascular Organ SystemCardiovascular PhysiologyCardiovascular systemCausalityCause of DeathCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeCessation of lifeCetacortCharacteristicsCircadian RhythmsCommunitiesCort-DomeCortefCortenemaCortisolCortisprayCortrilCuesCyclicityDeathDepressed moodDermacortDevelopmentDoctor of PhilosophyECB signalingEldecortEmotionalEmotionsEndocannabinoidsEndogenous CannabinoidsEnvironmentEnzyme GeneEnzymesEtiologyEventEvidence based interventionExerciseExertionFutureGoalsHealthHealth ExpendituresHeart DiseasesHeart RateHeart VascularHemostasisHemostatic functionHumanHydrocortisoneHydrocortoneHypertensionHytoneIlluminationIncidenceInterventionKnowledgeLabor ForcesLaboratoriesLeadLightLightingLinkLipidsMarrow plateletMeasuresMedication ManagementMelatoninMentorsMiceMice MammalsModerate ExerciseModern ManMoodsMurineMusNutracortNyctohemeral RhythmPathway interactionsPb elementPeriodicityPh.D.PhDPharmacologic ManagementPhasePhotoradiationPhysiologicPhysiologicalPhysiologyPlasmaPlasma SerumPlateletsPreventionProctocortProtocolProtocols documentationPsyche structurePsychosocial StressQuestionnairesRaceRacesReceptor ProteinRecoveryRecurrenceRecurrentReportingResearchRestReticuloendothelial System, Serum, PlasmaRhythmicityRiskRoleRotationSalivaryScheduleScientistSleepSleep Wake CycleStandardizationStressStrokeSystemTestingThrombocytesTimeTrainingTranslatingTwenty-Four Hour RhythmVariantVariationVascular Hypertensive DiseaseVascular Hypertensive DisorderWakefulnessWorkacute stressadulthoodagedagesattenuateattenuatesawakebiologicbiological adaptation to stressbrain attackcardiometaboliccardiometabolismcardioprotectantcardioprotectioncardioprotectivecardiovascular disordercardiovascular functioncardiovascular healthcareercaucasian Americancausationcerebral vascular accidentcerebrovascular accidentcircadiancircadian processcircadian rhythmicitycirculatory systemcostdaily biorhythmday shiftdepresseddevelopmentaldisease causationeCB systememotion regulationemotional regulationendocannabinoid signalingendocannabinoid systemendogenous cannabinoid systemhabituationhealth care expenditureheart disorderheavy metal Pbheavy metal leadhigh blood pressurehyperpiesiahyperpiesishypertensive diseasehypertensive disorderimprovedmedical expendituremedication therapy managementmentalmoderate physical activitymortalitynight shiftnight workparent grantpathwayplatelet functionproductivity losspsychosocialracialracial backgroundracial originreaction; crisisreceptorresponsesadnessshift workshiftworksleep to wake transitionsleep to wakefulness transitionsleep wakefulness cyclesleep/wake transitionssocial rolestress bufferingstress managementstress reactivitystress responsestress; reactionstressorstrokedstrokeswhite American
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Description preview
Project Summary
Cardiovascular (CV) disease is the leading cause of death in the US. Night and rotating shift work, ~20% of the
labor force, is associated with a greater incidence of both psychosocial stress and CV disease suggesting that
wakefulness and activity when the body is optimized for sleep and recovery is harmful to one’s health. Acute…
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