grant
Role of Bile Acids in Time-Restricted Feeding
Organization UNIVERSITY OF CALIFORNIA LOS ANGELESLocation LOS ANGELES, UNITED STATESPosted 1 Apr 2026Deadline 31 Mar 2030
NIHUS FederalResearch GrantFY20260-11 years oldAddressAppetiteAutoregulationBile Acid BiosynthesisBile Acid Biosynthesis PathwayBile AcidsBiomedical ResearchBiometricsBiometryBiostatisticsBlood PlasmaBoard CertificationBody TissuesBody WeightCP7ACRISPRCRISPR/Cas systemCYP7A1CYP7A1 geneCaloric RestrictionCatabolismCell Communication and SignalingCell SignalingCellular Metabolic ProcessChildChild YouthChildhoodChildren (0-21)CholesterolCholesterol HomeostasisCircadian RhythmsClinical ResearchClinical SciencesClinical StudyClustered Regularly Interspaced Short Palindromic RepeatsConfocal MicroscopyDataDedicationsDesire for foodDetergentsDevelopment PlansDevelopment and ResearchDietDietary CholesterolDietary FatsDiseaseDisorderDiurnal RhythmDrugsDyslipidemiasEatingEducational workshopEnzyme GeneEnzymesEthicsExhibitsFatsFatty acid glycerol estersFood IntakeFutureGI hormoneGLP-1GPBAR1GPBAR1 geneGastroenterologistGastrointestinal HormonesGene ExpressionGlp-1GoalsGrantHealthHepaticHigh Fat DietHomeostasisHormone secretionHumanInstitutionInstructionIntermediary MetabolismIntermittent fastingIntestinalIntestinesIntracellular Communication and SignalingKO miceKnock-out MiceKnockout MiceLinkLipidsLiverManuscriptsMass Photometry/Spectrum AnalysisMass SpectrometryMass SpectroscopyMass SpectrumMass Spectrum AnalysesMass Spectrum AnalysisMeasuresMediatingMediatorMedicationMentorsMetabolicMetabolic DiseasesMetabolic DisorderMetabolic PathwayMetabolic ProcessesMetabolismMiceMice MammalsModern ManMolecularMorphologyMurineMusNational Institutes of HealthNull MouseNyctohemeral RhythmPaperPathway interactionsPatternPharmaceutical PreparationsPhasePhysiciansPhysiologicPhysiologicalPhysiological HomeostasisPhysiologyPlasmaPlasma SerumPlayPreparationProceduresPublishingR & DR&DReceptor ProteinRegulationResearchResearch ResourcesResourcesReticuloendothelial System, Serum, PlasmaRoleScientistShapesSignal TransductionSignal Transduction SystemsSignalingSignaling MoleculeSpecialtyTGR5TestingTherapeuticThesaurismosisTimeTime-restricted eatingTime-restricted feedingTissuesTrainingTranslational ResearchTranslational ScienceTwenty-Four Hour RhythmUnited States National Institutes of HealthWorkWorkshopWritingabsorptionbile acid anabolismbile acid biosynthetic processbile acid formationbile acid metabolismbile acid synthesisbile metabolismbiological signal transductionbowelcalorie restrictioncareercareer developmentcell metabolismcellular metabaolismcholesterol metabolismcircadian processcircadian rhythmicitycombatdaily biorhythmdiet-associated obesitydiet-induced obesitydiet-related obesitydietarydietary lipiddietsdiurnal variationdrug/agentenergy balanceethicalfat metabolismfeedingfood Ingestionfood consumptionglucagon-like peptide 1gut hormonegut-derived hormonehepatic body systemhepatic organ systemhormonal regulationhormonal secretionhormone regulationimprovedinnovateinnovationinnovativeinsightinsulin sensitivitykidslipid metabolismmedical specialtiesmetabolism disordernew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapy approachesnew treatment approachnew treatment strategynovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapy approachpathwaypediatricpre-clinical studypreclinical studypreparationspreventpreventingprogramsreceptorresearch and developmentresponseside effectsocial roletargeted drug therapytargeted drug treatmentstargeted therapeutictargeted therapeutic agentstargeted therapytargeted treatmenttooltranslation researchtranslational investigationtrendwestern dietwestern-style dietwestern-type dietyoungster
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PROJECT SUMMARY/ABSTRACT
Dr. Alvin Chan is a board-certified pediatric gastroenterologist and physician-scientist dedicated to investigating
the regulatory role of bile acids in health and disease. His research focuses on how bile acids shape metabolic
processes. His long-term carer goal is to establish an independent research program exploring…
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