grant

Rodent Phenotyping Core

Organization UNIVERSITY OF IOWALocation IOWA CITY, UNITED STATESPosted 1 Sept 2016Deadline 30 Jun 2026
NIHUS FederalResearch GrantFY2025AcuteAddressAnimal HusbandryAnteriorAreaAssayAxonBioassayBiologicalBiological AssayBody TissuesCOVID-19CV-19CategoriesCollaborationsCommon Rat StrainsConsultConsultationsCoronavirus Infectious Disease 2019Cranial Nerve IIDevelopmentDissectionEducational workshopElectroretinographyExperimental DesignsEye diseasesFeesFluorescein AngiographyFundingFundusGoalsGonioscopyHousingHuman ResourcesIlluminationInjectionsIntraocular PressureInvestigationInvestigatorsIowaLightLightingManpowerMeasuresMiceMice MammalsMissionModelingMurineMusNational Institutes of HealthOcular TensionOptic NervePhenotypePhotographyPhotoradiationPhysiologic Intraocular PressureProceduresPupil light reflexRatRats MammalsRattusReproducibilityResearch PersonnelResearch ResourcesResearchersResourcesRetinaRetinal Ganglion CellsRodentRodentiaRodents MammalsScienceSecond Cranial NerveServicesSightSlideSystemTemperatureTestingTissuesTrainingUnited States National Institutes of HealthUniversitiesVisionVision TestsVision researchWorkshopautomated image analysisbehavior measurementbehavioral measurebehavioral measurementbiologicconsultationconsultscoronavirus disease 2019coronavirus disease-19coronavirus infectious disease-19deep learningdeep learning methoddeep learning strategydevelopmentalelectroretinogramequipment acquirementequipment acquisitionequipment investmentequipment procurementequipment purchaseequipment purchasingexperimentexperimental researchexperimental studyexperimentseye disorderinstrument acquisitioninstrument investmentinstrument procurementinstrument purchaseintra-ocular pressureinvestigator trainingmodel organismmultidisciplinaryocular diseaseocular disorderophthalmopathypandemicpandemic diseasepersonnelpupillary light reflexpupillary reflexresponseretinal ganglionsemen cryopreservationsperm cell cryopreservationsperm cryopreservationsperm freezingspermatozoa cryopreservationvision sciencevisual functionvisual science
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Full Description

PROJECT SUMMARY
The goal of the Rodent Phenotyping Core (RPC) is to increase the utility of mice and rats as

model organisms for vision research at The University of Iowa. The availability of a centralized

core for phenotyping will allow investigators to focus their resources on the science and

discoveries underlying vision research, rather than on training each lab’s personnel to perform

phenotyping. Such core-based services will yield more consistent and reproducible

phenotyping measures and in turn maximize the power of NEI-funded investigators to make

new discoveries.

The RPC will have the capability to perform detailed phenotyping of the anterior segment (slit-

lamp examination and photography, SD-OCT, gonioscopy, fluorescein angiography, and

intraocular pressure recording) and the posterior segment (fundus examination/photography,

electroretinogram, pupil light reflex, behavioral measurements of vision, acute suppression of

activity by light, and testing of optokinetic response).

Grant Number: 5P30EY025580-10
NIH Institute/Center: NIH

Principal Investigator: Michael Anderson

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