grant
Regulation of Progenitor Cell Plasticity in Lung Development and Disease-Repair
Organization COLUMBIA UNIVERSITY HEALTH SCIENCESLocation NEW YORK, UNITED STATESPosted 1 Jul 2023Deadline 30 Jun 2030
NIHUS FederalResearch GrantFY202521+ years oldAddressAdultAdult HumanAlveolusBehaviorBiologyBronchial AlveolusCOPDCell BodyCell CompartmentationCell CompartmentationsCellsChronic DiseaseChronic IllnessChronic Obstruction Pulmonary DiseaseChronic Obstructive Lung DiseaseChronic Obstructive Pulmonary DiseaseDevelopmentDiseaseDisorderEpidemiological dataEpidemiology dataFutureGeneralized GrowthGenetic ModelsGrowthHumanKnowledgeLinkLungLung DiseasesLung Respiratory SystemLung damageModern ManNatural regenerationOrganoidsPerinatalPeripartumPneumologyPneumonologyProcessProgenitor CellsPulmonary DiseasesPulmonary DisorderPulmonary MedicinePulmonologyRegenerationRegulationResearch ProposalsResolutionTechnologyTherapeutic InterventionTissue Growthadulthoodairway epithelial stem cellsairway progenitorairway stem cellschronic disorderchronic obstructive pulmonary disordercohortdevelopmentaldisease of the lungdisorder of the lungepidemiologic dataepithelial progenitorepithelial progenitor cellepithelial stem cellfetalgenetic epidemiologic studygenetic epidemiologyhuman diseaseinsightintervention therapyintrauterine environmentintrauterine milieulung developmentlung disorderlung injurylung progenitorlung repairlung stem celllung tissue repairlung tissue stem celllung-specific stem cellmouse geneticsmouse modelmurine modelneonatal humanontogenypreventpreventingprogenitor cells in the lungprogenitors in the lungprogramspulmonary damagepulmonary injurypulmonary progenitorpulmonary repairpulmonary stem cellpulmonary tissue damagepulmonary tissue injuryregeneraterepairrepairedresolutionsrespiratory progenitorrespiratory stem cellstem cellsstem cells in the airwaystem cells in the lung
Description preview
ABSTRACT
Despite much progress in the field of lung biology and pulmonary medicine, a major gap of knowledge
remains in the lack of a broader understanding of the composition and regulation of the lung stem cell
compartment and its behavior in disease and regeneration-repair. Recent studies bring an additional
complexity to the scenario, as they…
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