grant
Regulation Of Childhood Growth
Organization EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENTLocation UNITED STATES
NIHUS FederalResearch GrantFY20250-11 years old90-kD Subunit Transcription Factor IIIBAKTAdverse effectsAffectAkt proteinAntibody FragmentsAppearanceB-Related Factor 1BRF GeneBRF1BRF1 HomologBRF1 Homolog Subunit of RNA Polymerase III Transcription Initiation Factor IIIBBRF1 geneBasal Transcription FactorBasal transcription factor genesBindingBody TissuesBone DiseasesBone GrowthC-Type Natriuretic PeptideCNP-22CYP26 proteinCYP26A1CYP450 4-hydroxylaseCartilageCartilaginous TissueCell BodyCell Communication and SignalingCell Growth in NumberCell MultiplicationCell ProliferationCell SignalingCell-Extracellular MatrixCellsCellular ProliferationChildChild YouthChildhoodChildren (0-21)Chimera ProteinChimeric ProteinsChondrocytesChondrogenesisChromosomal, Gene, or Protein AbnormalityComplexCytogenetic or Molecular Genetic AbnormalityDNA Synthesis FactorDiseaseDisorderECMEndocrineEndosomesEndothelial Cell Growth FactorEpigeneticEpigenetic ChangeEpigenetic MechanismEpigenetic ProcessEpiphyseal PlateEpiphysial cartilageEstrogensExtracellular MatrixFGFFUS-1 ProteinFaceFaciesFailureFamilyFamily StudyFibroblast Growth FactorFibroblast Growth Factor Gene FamilyFibroblast Growth Regulatory FactorFormerly TAF3CFusion 1 ProteinFusion ProteinGTF3BGene variantGeneral Transcription Factor GeneGeneral Transcription Factor IIIB 90kD SubunitGeneral Transcription FactorsGeneralized GrowthGenesGeneticGenetic AbnormalityGenetic DiseasesGlucocorticoidsGoalsGrowthGrowth DisordersGrowth PlateGrowth and DevelopmentGrowth and Development functionHeightHereditaryHumanHuman GeneticsHumulin RHypercalcemic Hormone of MalignancyHypoglycemiaImmunoglobulin FragmentsImpairmentIn VitroInheritedInhibition of Cell ProliferationInitiation CodonInitiator CodonInjectionsInsulinIntracellular Communication and SignalingInvestigationLeannessLinkMicroRNAsMissense MutationModern ManMolecularMolecular AbnormalityMolecular InteractionNegative Control of Cell ProliferationNegative Regulation of Cell ProliferationNovolin RP450RAIPDGFA associated protein 2PTH Like Tumor FactorPTH-Like ProteinPTH-Related PeptidePTHrPParathyroid Hormone Like Tumor FactorParathyroid Hormone-Like HormoneParathyroid Hormone-Like ProteinParathyroid Hormone-Related PeptidePopulation GrowthProtein Kinase BProto-Oncogene Proteins c-aktRA-4-hydroxylaseRAC-PK proteinReaderReceptosomesRecombinant Parathyroid Hormone-Related ProteinRecombinantsRegular InsulinRegulationRenal CellRestRetinoic Acid AgentRetinoic Acid and DerivativesRetinoidsRoleSignal TransductionSignal Transduction SystemsSignalingStart CodonSyndromeSystemTAF3B2TAF3B2 GeneTAF3CTAFIII90TATA Box Binding Protein -Associated Factor 3CTATA Box Binding Protein -Associated Factor RNA Polymerase III Subunit 2TATA Box-Binding Protein-Associated Factor, RNA Polymerase III, Subunit 2TBP-Associated Factor RNA Polymerase III 90kDTBP-Associated Factor, RNA Polymerase III, 90-kDTF3B90TFIIIB90 GeneTherapeutic EstrogenThinnessTissue GrowthTissuesTranscription Factor Proto-OncogeneTranscription Initiation Factor IIIBTranscription factor genesTumor Hypercalcemic FactorVariantVariationWNT Signaling PathwayWNT signalingWorkallelic variantbiological signal transductionbonebone disorderbone turnoverc-akt proteincartilage matrix glycoproteincartilage matrix proteincytochrome P-450 CYP26cytochrome P450 4-hydroxylaseepigeneticallyexome sequencingexome-seqfacesfacialgenetic conditiongenetic disordergenetic variantgenomic varianthBRFhistone modificationhypoglycemichypoglycemic episodesinsightkidney cellkidsknock-downknockdownmalformationmatrilin 3matrilin-1matrillin-1miRNAmissense single nucleotide polymorphismmissense single nucleotide variantmissense variantmolecular aberrationsnew therapeutic approachnew therapeutic interventionnew therapeutic strategiesnew therapy approachesnew treatment approachnew treatment strategynovel therapeutic approachnovel therapeutic interventionnovel therapeutic strategiesnovel therapy approachontogenyparacrineparathyroid hormone-related proteinpediatricpharmacologicprotein complexprotein expressionproto-oncogene protein RACproto-oncogene protein aktrac protein kinaserelated to A and C-proteinretinoic acid 4-hydroxylaseretinoic acid-metabolizing enzymeskeletalskeletal dysplasiasocial roletargeted drug therapytargeted drug treatmentstargeted therapeutictargeted therapeutic agentstargeted therapytargeted treatmenttraffickingtranscription factoryoungster
Description preview
Children grow taller because their bones grow longer. This bone elongation results from chondrogenesis in the growth plate, a thin layer of cartilage found near the ends of children’s bones. Growth plate chondrogenesis is controlled by multiple endocrine, paracrine, extracellular matrix-related, and intracellular regulatory systems. Our group has…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click