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Quantitative Electrophysiology to Link Neuroplasticity, Brain State, and Behavioral Change in Human Visual Cortex
Organization STANFORD UNIVERSITYLocation STANFORD, UNITED STATESPosted 1 Jun 2023Deadline 31 Dec 2025 ⚠️
NIHUS FederalResearch GrantFY2025ASDAddressAffectAmblyopiaAnimal ModelAnimal Models and Related StudiesAnimalsApoplexyAreaArousalAttentionAttention Deficit DisorderAutismAutistic DisorderBayesian ModelingBayesian adaptive designsBayesian adaptive modelsBayesian belief networkBayesian belief updating modelBayesian frameworkBayesian hierarchical modelBayesian network modelBayesian nonparametric modelsBayesian spatial data modelBayesian spatial image modelsBayesian spatial modelsBayesian statistical modelsBayesian tracking algorithmsBehaviorBehavior Conditioning TherapyBehavior ModificationBehavior TherapyBehavior TreatmentBehavioralBehavioral Conditioning TherapyBehavioral ModificationBehavioral TherapyBehavioral TreatmentBiologyBlindnessBrainBrain Nervous SystemBrain TraumaBrain Vascular AccidentCNS plasticityCatsCats MammalsCell Communication and SignalingCell SignalingCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeCerebrumChronic pain syndromeClinicClinicalCognitive DiscriminationComputer ModelsComputerized ModelsConditioning TherapyContrast SensitivityDataData SetDevelopmentDiminished VisionDiscriminationDiseaseDisorderDomestic CatsEEGEarly Infantile AutismElectroencephalogramElectroencephalographyElectrophysiologyElectrophysiology (science)EmotionsEncephalonEnvironmentFeedbackFeline SpeciesFelis catusFelis domesticaFelis domesticusFelis sylvestris catusFutureGoalsHumanImpairmentInfantile AutismIntracellular Communication and SignalingInvestigatorsKanner's SyndromeKnowledgeLeadLearningLeftLinkLow VisionMR ImagingMR TomographyMRIMRIsMagnetic Resonance ImagingMeasuresMediatingMedical Imaging, Magnetic Resonance / Nuclear Magnetic ResonanceMedical RehabilitationMental DepressionMentorsMethodsModelingModern ManMotor CortexNMR ImagingNMR TomographyNerve CellsNerve UnitNeural CellNeurocyteNeuronal PlasticityNeuronsNeurophysiology / ElectrophysiologyNeurosciencesNoiseNuclear Magnetic Resonance ImagingOpticsPartial SightPatientsPb elementPerceptionPhoriasPhysiologyPrimary visual cortexProcessPsychophysicsRecoveryReduced VisionRegulationRehabilitationRehabilitation therapyResearchResearch PersonnelResearch ProposalsResearchersRoleScotomaSensorySightSignal TransductionSignal Transduction SystemsSignalingSourceSquintStrabismusStressStriate CortexStriate areaStrokeStudy modelsSubnormal VisionSynapsesSynapticSynaptic plasticityTechniquesTestingTimeTrainingTraumatic Brain InjuryTreatment EfficacyVisionVision DisordersVisual Contrast SensitivityVisual CortexVisual DisorderVisual Evoked PotentialsVisual Evoked ResponseVisual Field DisorderVisual FieldsVisual attentionVisual evoked cortical potentialVisual field scotomaVisual impairmentVisuospatialWorkZeugmatographyaddictionaddictive disorderarea striataattention modulationattentional modulationauthorityautism spectral disorderautism spectrum disorderautistic spectrum disorderbehavior interventionbehavioral interventionbiological signal transductionbrain attackbrain controlcatscentral nervous system plasticitycerebralcerebral vascular accidentcerebral vision impairmentcerebral visual impairmentcerebrovascular accidentcomputational modelingcomputational modelscomputer based modelscomputerized modelingcortical vision impairmentcortical visual impairmentdepressiondevelopmentalelectrophysiologicalexperienceexperimentexperimental researchexperimental studyexperimentseye fieldfrontal eye fieldsheavy metal Pbheavy metal leadin vivoinattentioninattentivenessinsightintervention efficacymodel of animalmouse modelmurine modelneuralneural controlneural correlateneural plasticityneural regulationneuromodulationneuromodulatoryneuronalneurophysiologicalneurophysiologyneuroplasticneuroplasticityneuropsychiatricneuropsychiatric diseaseneuropsychiatric disorderneuropsychiatryneuroregulationnovelopticalpreconditioningprogramspsychophysicalrehab therapyrehabilitativerehabilitative therapyrepetitive transcranial magnetic stimulationresponseretinotopicsocial rolestrokedstrokessynapsetherapeutic efficacytherapy efficacytraumatic brain damagevision impairmentvision lossvisual controlvisual corticalvisual cortical plasticityvisual field defectvisual functionvisual lossvisual plasticityvisual processvisual processingvisual spatialvisually impaired
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PROJECT SUMMARY / ABSTRACT
Rehabilitation of central visual disorders like amblyopia and cortical visual impairment depends on synaptic
plasticity, the changes in synaptic connections between neurons in the brain. A major regulator of synaptic plas-
ticity is brain state - the moment-to-moment fluctuations in attention, arousal, emotions and other…
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