grant
Psychopharmacological effects of cannabidiol on responses to stress and nicotine withdrawal
Organization UNIVERSITY OF MINNESOTALocation MINNEAPOLIS, UNITED STATESPosted 30 Sept 2010Deadline 28 Feb 2029
NIHUS FederalResearch GrantFY2025AcuteAddressAeroseb-HCAffectiveAgeAgitationAnxietyAttentionAttenuatedBehavioralCannabidiolCannabisCardiac ChronotropismCardiovascularCardiovascular Body SystemCardiovascular Organ SystemCardiovascular systemCetacortClinic VisitsCollaborationsCort-DomeCortefCortenemaCortisolCortisprayCortrilDermacortDifferences between sexesDiffers between sexesDoseDouble-Blind MethodDouble-Blind StudyDouble-BlindedDouble-Masked MethodDouble-Masked StudyDropsEldecortEnsureEpidiolexExhibitsExposure toFundingGenderHealthHeart RateHeart VascularHormonalHormonal ChangeHourHydrocortisoneHydrocortoneHypophysisHypophysis CerebriHypothalamic structureHypothalamusHytoneIndividualIndividual DifferencesLinkMarketingMeasuresMethodologyMethodsMoodsMotivationNicotine WithdrawalNutracortOpiatesOpioidOralOutcome MeasureParticipantPatient Self-ReportPatternPhysiologicPhysiologicalPituitaryPituitary GlandPituitary Nervous SystemPlacebosProceduresProctocortProtocolProtocols documentationPsychomotor AgitationPsychomotor ExcitementPsychomotor HyperactivityPsychomotor RestlessnessPublic HealthRandomizedRecoveryRegulationRelapseReportingReproducibilityResearchResearch DesignRestRestlessnessSalivarySample SizeSamplingSelf-ReportSex DifferencesSexual differencesSham TreatmentSiteSmokerSmokingSmoking Cessation InterventionStandardizationStressStudy SubjectStudy TypeSubgroupSurvey InstrumentSurveysSymptomsTestingTobaccoTobacco CessationTobacco ConsumptionTobacco DependenceTobacco Use CessationTobacco smokingTobacco smoking behaviorTobacco useVariantVariationVisitWitWithdrawalWithdrawal SymptomWomanabuse liabilityabuse potentialacute stressagesattenuateattenuatesbehavior measurementbehavioral measurebehavioral measurementbiobehaviorbiobehavioralbiological adaptation to stresscannabis usercirculatory systemcravingemotion regulationemotional regulationhypothalamicmarijuana usermeasurable outcomemennegative affectnegative affectivitynicotine consumptionnicotine usenicotine usernon-smokernon-smokingnonsmokernonsmokingnoveloutcome measurementpharmacologicphytocannabinoidpower analysisprimary outcomepsychobiologicpsychobiologicalpsychopharmacologicpsychopharmacologicalrandomisationrandomizationrandomly assignedreaction; crisisrecruitrelapse predictionresponsesexsex based differencessex-dependent differencessex-related differencessex-specific differencessham therapysimulationsmoking cessation treatmentstress responsestress; reactionstressorstudy designtobacco addictiontobacco dependenttobacco product usetobacco user
Description preview
Summary
Despite advances in tobacco smoking cessation interventions (pharmacological and behavioral), most
smokers do not succeed at quitting, creating a major public health burden. Stress is one of the most
commonly reported precipitants of tobacco craving and relapse. Tobacco withdrawal is associated with
escalation of negative affect symptoms;…
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