grant
Proteostasis regulators in blood cell development and function
Organization DIVISION OF BASIC SCIENCES - NCILocation UNITED STATES
NIHUS FederalResearch GrantFY202520S Catalytic Proteasome20S Core Proteasome20S Proteasome20S ProteosomeAML - Acute Myeloid LeukemiaAPF-1ATP-Dependent Proteolysis Factor 1Acute Myeloblastic LeukemiaAcute Myelocytic LeukemiaAcute Myelogenous LeukemiaAcute T Cell LeukemiaAcute T-Cell Lymphoblastic LeukemiaAcute T-Cell Lymphocytic LeukemiaAcute T-Lymphocytic LeukemiaAgeAnimal ModelAnimal Models and Related StudiesApoptosisApoptosis PathwayAutoregulationBloodBlood CellsBlood Precursor CellBlood Reticuloendothelial SystemBody TissuesBone MarrowBone Marrow Reticuloendothelial SystemCancersCell BodyCell Communication and SignalingCell LineageCell SignalingCellsCellular biologyChronicDefectDevelopmentDiseaseDisorderDysfunctionFailureFunctional disorderGenerationsGenomicsGoalsHMG-20HematopoiesisHematopoieticHematopoietic Cell TumorHematopoietic Cellular Control MechanismsHematopoietic MalignanciesHematopoietic NeoplasmsHematopoietic Neoplasms including LymphomasHematopoietic Progenitor CellsHematopoietic TumorHematopoietic and Lymphoid Cell NeoplasmHematopoietic and Lymphoid NeoplasmsHematopoietic stem cellsHigh Mobility Protein 20HomeostasisHumanImmuneImmunesImmunityImpairmentInflammationIntracellular Communication and SignalingInvestigationKnowledgeMacropainMacrophageMacroxyproteinaseMaintenanceMalignantMalignant - descriptorMalignant Hematopoietic NeoplasmMalignant NeoplasmsMalignant TumorMammalian CellMediatorModern ManMolecularMulticatalytic ProteinaseMuscleMuscle TissueMφPathogenesisPathway interactionsPeripheral Blood CellPhysiological HomeostasisPhysiopathologyPost-Translational Modification Protein/Amino Acid BiochemistryPost-Translational ModificationsPost-Translational Protein ModificationPost-Translational Protein ProcessingPosttranslational ModificationsPosttranslational Protein ProcessingPrecursor T Lymphoblastic LeukemiaProcessProgrammed Cell DeathProsomeProteasomeProteasome Endopeptidase ComplexProtein ModificationProteinsProteomeProteomicsProteosomeResearchRoleShapesSignal PathwaySignal TransductionSignal Transduction SystemsSignalingStressSystemT-Cell Type Acute LeukemiaT-CellsT-LymphocyteT-lineage acute lymphoblastic leukemiaTestingTissuesUbiquitinViral DiseasesVirus Diseasesacute granulocytic leukemiaacute granulocytic leukemia cellacute myeloblastic leukemia cellacute myelocytic leukemia cellacute myelogenous leukemia cellacute myeloid leukemiaacute myeloid leukemia cellacute nonlymphocytic leukemia cellagesbiological signal transductionblood cancerblood cell formationblood cell progenitorblood progenitorblood stem cellblood-forming stem cellbone qualitycancer of bloodcancer of the bloodcell biologydesigndesigningdevelopmentalexhaustiongenome integritygenomic integrityhematopoietic progenitorhematopoietic stem progenitor cellhemopoietichemopoietic progenitorhemopoietic stem cellmalignancymodel of animalmulticatalytic endopeptidase complexmuscularneoplasm/cancernovelpathophysiologypathwayprogenitor cell poolprogenitor cell populationprogenitor poolprogenitor populationprotein homeostasisproteostasisresponsesocial rolestem and progenitor cell populationstem cell poolstem cell populationthymocytethymus derived lymphocytetranscriptomicsviral infectionvirus infectionvirus-induced disease
Description preview
The goal of research in my lab is to better understand the process of blood cell generation from hematopoietic stem cells (HSC) in the bone marrow as well as the differentiation of committed blood cell lineages and to apply this knowledge to elucidate the mechanisms of blood cell dysfunction and malignancy. While it is widely appreciated that…
🔒
Start 7-day free trial — $29.99/mo →Full details available on the Agency plan
Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link — plus alerts, pipeline tracking, and CSV export.
Agency Plan
7-day free trialUnlock procurement & grants
Upgrade to access active tenders from World Bank, UNDP, ADB and more — with email alerts and pipeline tracking.
$29.99 / month
- 🔔Email alerts for new matching tenders
- 🗂️Track tenders in your pipeline
- 💰Filter by contract value
- 📥Export results to CSV
- 📌Save searches with one click