πŸ—‚οΈ

Archived grant β€” no longer open

This grant has closed and is kept as a historical reference. Browse current grants for active opportunities.

grant

Protection Against Nosocomial Infections After Severe Burn Injury Through Trained Immunity

Organization VANDERBILT UNIVERSITY MEDICAL CENTERLocation NASHVILLE, UNITED STATESPosted 1 May 2021Deadline 30 Apr 2026 ⚠️
NIHUS FederalResearch GrantFY2025AgonistBlood leukocyteBurn injuryBurnsCause of DeathCell BodyCell Communication and SignalingCell SignalingCellsDifferential Gene ExpressionDrug TargetingDysfunctionExposure toFunctional disorderGeneticGoalsHigh PrevalenceHomolog of Drosophila TOLLHospital AdmissionHospital InfectionsHospital acquired infectionHospitalizationHumanImmuneImmune DiseasesImmune DisordersImmune DysfunctionImmune Modulation TherapyImmune System DiseasesImmune System DisorderImmune System DysfunctionImmune System and Related DisordersImmune mediated therapyImmune memoryImmune responseImmune systemImmunesImmunityImmunologic DiseasesImmunologic MemoryImmunological DiseasesImmunological DysfunctionImmunological MemoryImmunological System DysfunctionImmunologically Directed TherapyImmunomodulationImmunotherapeutic agentImmunotherapyImpairmentInfectionInfection preventionIntracellular Communication and SignalingKnowledgeLeukocytesLeukocytes Reticuloendothelial SystemLifeMacrophageMarrow leukocyteMediatingMetabolicMiceMice MammalsMitochondriaModern ManModificationMolecularMurineMusMyeloid CellsMφNosocomial InfectionsOxidative StressPatientsPhysiopathologyPredispositionPrevent infectionResearchResistanceResistance to infectionSignal PathwaySignal TransductionSignal Transduction SystemsSignalingStimulusSusceptibilityTLR proteinTLR4TLR4 geneTechniquesTherapeuticTissue-Specific Differential Gene ExpressionTissue-Specific Gene ExpressionToll HomologueToll-Like Receptor Family GeneToll-like receptorsTrainingWhite Blood CellsWhite Cellanamnestic reactionanti-microbialantibiotic resistant pathogenantimicrobialbiological signal transductionburn modelburnedclinical applicabilityclinical applicationclinical developmentclinical relevanceclinically relevantdetermine efficacydrug resistant pathogenefficacy analysisefficacy assessmentefficacy determinationefficacy evaluationefficacy examinationevaluate efficacyexamine efficacyhost responseimmune drugsimmune modulationimmune modulatory therapiesimmune modulatory treatmentimmune regulationimmune regulation therapyimmune regulation treatmentimmune regulatory therapyimmune system responseimmune therapeutic approachimmune therapeutic interventionsimmune therapeutic regimensimmune therapeutic strategyimmune therapyimmune-based therapeuticsimmune-based therapiesimmune-based treatmentsimmune-modulation treatmentimmuno therapyimmunologic reactivity controlimmunologic therapeuticsimmunomodulation therapyimmunomodulation treatmentimmunomodulator therapiesimmunomodulator treatmentimmunomodulator-based therapiesimmunomodulatoryimmunomodulatory biologicsimmunomodulatory therapiesimmunomodulatory treatmentimmunoregulationimmunoregulatoryimmunoregulatory therapyimmunoregulatory treatmentimmunoresponseimmunotherapeuticsimmunotherapy agentimprovedinfection resistanceinstitutional infectionmitochondrialpathogenpathophysiologyprogramsresistantresponsesecondary immune responseserious burnssevere burnstherapeutic immunomodulationtherapeutic immunoregulationtherapeutic targettoll-like receptor 4white blood cellwhite blood corpuscle

Applications closed.

Description preview

PROJECT SUMMARY
Nosocomial infections remain the leading cause of death in severely burned patients due to barrier loss, im-
paired immunity, and high prevalence of antibiotic resistant pathogens. Immunomodulatory strategies aimed at
augmenting the host response are greatly needed. Evidence suggests that Toll-like receptor (TLR) agonists
hold…

πŸ”’

Full details available on the Agency plan

Unlock the complete grant description, eligibility criteria, contract value, evaluation details and apply link β€” plus alerts, pipeline tracking, and CSV export.

Start 7-day free trial β€” $29.99/mo β†’

Agency Plan

7-day free trial

Unlock procurement & grants

Upgrade to access active tenders from World Bank, UNDP, ADB and more β€” with email alerts and pipeline tracking.

$29.99 / month

  • πŸ””Email alerts for new matching tenders
  • πŸ—‚οΈTrack tenders in your pipeline
  • πŸ’°Filter by contract value
  • πŸ“₯Export results to CSV
  • πŸ“ŒSave searches with one click
Start 7-day free trial β†’

Explore more

πŸ“ More grants in UNITED STATES🏷 More NIH opportunities🏷 More US Federal opportunities🏷 More Research Grant opportunities🏒 All nih_reporter opportunities
Protection Against Nosocomial Infections After Severe Burn Injury Through Trained Immunity β€” VANDERBILT UNIVERSITY MEDIC | Dev Procure