grant

Project 2-Optimization of Post-Transplant care via Biomarkers and Behavioral Interventions

Organization JOHNS HOPKINS UNIVERSITYLocation BALTIMORE, UNITED STATESPosted 1 Feb 2019Deadline 31 May 2029
NIHUS FederalResearch GrantFY2025AbstinenceAdjuvantAdvocateAffectAgeAlcohol Chemical ClassAlcohol DrinkingAlcohol associated hepatitisAlcohol consumptionAlcohol hepatitisAlcohol induced hepatitisAlcohol related hepatitisAlcoholic HepatitisAlcoholic Liver DiseasesAlcoholsAttentionBehavior Conditioning TherapyBehavior ModificationBehavior TherapyBehavior TreatmentBehavioral Conditioning TherapyBehavioral ModificationBehavioral TherapyBehavioral TreatmentBiological MarkersCOVID crisisCOVID epidemicCOVID pandemicCOVID-19 crisisCOVID-19 epidemicCOVID-19 eraCOVID-19 global health crisisCOVID-19 global pandemicCOVID-19 health crisisCOVID-19 pandemicCOVID-19 periodCOVID-19 public health crisisCOVID-19 yearsCaringChronicClinicClinicalClinical ProtocolsCohort StudiesCombination Drug TherapyCommunicationConcurrent StudiesConditioning TherapyCosts and BenefitsDataDiagnosisDissemination and ImplementationDrug TherapyEarly treatmentEnrollmentEquilibriumEquityEtOH drinkingEtOH useEthanol-induced hepatitisFaceFatigueFundingGoalsGraft RejectionHarm MinimizationHarm ReductionHepatic DisorderHepatic TransplantationHepatologyHomeHospital AdmissionHospitalizationHospitalsIndividualInstitutionInterventionIntervention StrategiesIntervention TrialInterventional trialInterviewKnowledgeLack of EnergyLiverLiver GraftingLiver TransplantLiver diseasesMedicalMethodsModelingN-acetylhomotaurineNalorexNaltrexoneNemexinObservation researchObservation studyObservational StudyObservational researchOperative ProceduresOperative Surgical ProceduresOrganOutcomeParticipantPatient ParticipationPatientsPharmacological TreatmentPharmacotherapyPhasePolychemotherapyProviderPsychiatristRandomized, Controlled TrialsReViaRecommendationRelapseReportingResearchResearch ResourcesResourcesRisk FactorsSARS-CoV-2 epidemicSARS-CoV-2 global health crisisSARS-CoV-2 global pandemicSARS-CoV-2 pandemicSARS-coronavirus-2 epidemicSARS-coronavirus-2 pandemicScheduleSevere Acute Respiratory Syndrome CoV 2 epidemicSevere Acute Respiratory Syndrome CoV 2 pandemicSevere acute respiratory syndrome coronavirus 2 epidemicSevere acute respiratory syndrome coronavirus 2 pandemicShapesSocietiesSpecialistSurgicalSurgical InterventionsSurgical ProcedureSurgical complicationSystemTechniquesTechnology AssessmentTimeTrainingTransplant RecipientsTransplant RejectionTransplantationTransplantation RejectionUnited StatesVivitrolWorkabstaining from alcoholabstaining from ethanolabstinence from alcoholabstinence from ethanolacamprosateacamprostateaddictionaddictive disorderagesalcohol abstinencealcohol abuse therapyalcohol abuse treatmentalcohol effectalcohol induced hepatic injuryalcohol induced liver disorderalcohol induced liver injuryalcohol ingestionalcohol intakealcohol interventionalcohol product usealcohol relapsealcohol related liver diseasealcohol related researchalcohol researchalcohol riskalcohol treatmentalcohol usealcohol use disorderalcohol-associated liver diseasealcohol-induced hepatic dysfunctionalcohol-induced liver diseasealcohol-induced liver dysfunctionalcohol-mediated liver dysfunctionalcohol-mediated liver injuryalcohol-related liver diseasealcoholic beverage consumptionalcoholic drink intakealcoholic liver injurybalancebalance functionbehavior interventionbehavioral interventionbio-markersbiologic markerbiomarkerbrief interventionbrief therapybrief treatmentclinical carecohortcombination chemotherapycombination pharmacotherapycoronavirus disease 2019 crisiscoronavirus disease 2019 epidemiccoronavirus disease 2019 global health crisiscoronavirus disease 2019 global pandemiccoronavirus disease 2019 health crisiscoronavirus disease 2019 pandemiccoronavirus disease 2019 public health crisiscoronavirus disease crisiscoronavirus disease epidemiccoronavirus disease pandemiccoronavirus disease-19 global pandemiccoronavirus disease-19 pandemicdrug interventiondrug treatmentearly therapyenrollethanol abstinenceethanol consumptionethanol drinkingethanol effectethanol induced hepatic injuryethanol induced liver disorderethanol induced liver injuryethanol ingestionethanol intakeethanol liver diseaseethanol product useethanol relapseethanol researchethanol useethanol use disorderethanol-induced hepatic dysfunctionethanol-induced liver diseaseethanol-induced liver dysfunctionethanol-mediated liver dysfunctionethanol-mediated liver injuryevidence baseexperiencefacesfacialhepatic body systemhepatic diseasehepatic organ systemhepatopathyhomeshospital re-admissionhospital readmissionimprovedindexinginterdisciplinary approachinterestliver disorderliver transplantationmortalitymotivational enhancement therapymotivational interviewmultidisciplinary approachpandemicpandemic diseasepeer supportpharmaceutical interventionpharmacological interventionpharmacological therapypharmacology interventionpharmacology treatmentpharmacotherapeuticspost-transplantpost-transplantationposttransplantposttransplantationpractice settingpreventpreventingprogramspsychosocialrandomized control trialre-admissionre-hospitalizationreadmissionrehospitalizationrelapse riskresidenceresidential buildingresidential sitesafety outcomessevere acute respiratory syndrome coronavirus 2 global health crisissevere acute respiratory syndrome coronavirus 2 global pandemicsurgerysurgery complicationsurvival outcometransplanttransplant patienttreatment servicesyounger age
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PROJECT SUMMARY
Project 2 of the Johns Hopkins DELTA Center for Alcohol Research focuses on studying and implementing

evidence-based alcohol use disorder (AUD) interventions in the post-transplant setting. Alcohol-associated

liver disease (ALD) is the leading indication for liver transplants (LT) in the United States. Our group and others

have…

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