grant
Prenatal chemical exposures, childhood adversity, resilience and risk of depression
Organization WASHINGTON UNIVERSITYLocation SAINT LOUIS, UNITED STATESPosted 26 Sept 2025Deadline 30 Jun 2030
NIHUS FederalResearch GrantFY20250-11 years old21+ years oldAdolescentAdolescent YouthAdultAdult HumanAffectAgeAnxietyAttentionCausalityChemical ExposureChemicalsChildChild Behavior ChecklistChild Behavioral ChecklistChild YouthChildhoodChildhood Behavior ChecklistChildren (0-21)Children Behavior ChecklistClothingCommunitiesDataDeveloping fetusDisproportionate number of femalesDisproportionate number of womenDisproportionately affects femalesDisproportionately affects womenDisproportionately impacts femalesDisproportionately impacts womenDisproportionately in femalesDisproportionately in womenEducationEducational aspectsElectronicsEmotional DepressionEndocrine disruptionEpidemiologic ResearchEpidemiologic StudiesEpidemiological StudiesEpidemiology ResearchEstersEtiologyExposure toFamily RelationsFamily RelationshipFetal DevelopmentFire RetardantsFlame RetardantsFurnitureGestationHomeHouseholdImpoverishedIndividualIntervention StrategiesJointsLinkLos AngelesMaternal HealthMental DepressionMental HealthMental Health ServicesMental HygieneMental Hygiene ServicesMorbidityMorbidity - disease rateMothersNHANESNational Health and Nutrition Examination SurveyOrganophosphatesOutcomeParentsPhasePost-Natal DepressionPost-Partum DepressionPost-partum WomenPostnatal DepressionPostpartum DepressionPostpartum PeriodPostpartum WomenPovertyPredispositionPregnancyPregnant WomenPrevalencePreventative strategyPrevention strategyPreventive strategyPsychological HealthReportingRiskRisk FactorsRoleSeveritiesSingle ParentStressSusceptibilityTimeWomanadolescent depressionadolescents with depressionadulthoodadverse childhood eventsadverse childhood experiencesagesbiological sexbuilding materialscausationcenter for epidemiological studies depression scalechild depressionchildhood adversitychildhood depressionchildhood onset depressioncohortconsumer productdepressed adolescentsdepressed motherdepressiondepression in adolescencedepression symptomdepressivedepressive symptomsdisease causationearly adversityearly childhoodearly childhood adversityearly life adversityelectronicelectronic deviceendocrine disruptingenvironmental chemicalepidemiologic investigationepidemiology studyexpectant motherexpectant womenexpecting motherexpecting womenexperienceexposed in uterofemale biasfemale predominancefemale preponderancefetal exposurefood insecurityhealth care servicehomesin uteroin utero exposureindividuals who are pregnantintergenerationalintra-uterine environmental exposureintrauterine environmental exposurejuvenilejuvenile humankidsmalleable riskmaternal depressionmaternal riskmental health caremodifiable riskneurotoxicnext generationpandemicpandemic diseaseparentpediatricpediatric adversitypediatric depressionpeople who are pregnantperceived stressperception of stressperinatal depressionperipartum depressionpolybrominated biphenyl etherpolybrominated diphenyl etherpoor health outcomepost-partumpredominance in femalespredominance in womenpreferencepregnant femalespregnant motherspregnant peoplepregnant populationsprenatalprenatal exposureprenatally exposedprotective factorspublic health interventionpublic health prioritiesreduced health outcomeresilienceresilience scaleresiliency scaleresilientself-reported stresssexsocial rolestress perceptionthose who are pregnantunbornwomen who are pregnantwomen's predominancewomen's preponderanceworse health outcomeyoungsteryouth depression
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Depression is the leading cause of mental-health related morbidity worldwide and approximately 19.4 million US adults and 3.8 million US adolescents are affected annually. Emerging evidence suggests that prenatal exposure to legacy (polybrominated diphenyl ethers, PBDEs) and replacement (organophosphate esters, OPEs) flame retardant chemicals…
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