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Precision Pharmacogenomic Perioperative Prediction
Organization PORTLAND VA MEDICAL CENTERLocation PORTLAND, UNITED STATESPosted 1 Feb 2023Deadline 30 Sept 2025 ⚠️
VANIHUS FederalResearch GrantFY2025ACE InhibitorsAI systemAcetylsalicylic AcidAdrenergic beta-AntagonistsAdrenergic beta-BlockersAdverse drug eventAffectAnaphylactic ReactionAnaphylactic ShockAnaphylaxisAnesthestic DrugsAnesthetic AgentsAnesthetic DrugsAnestheticsAngiotensin I-Converting Enzyme InhibitorsAngiotensin ReceptorAngiotensin-Converting Enzyme AntagonistsAngiotensin-Converting Enzyme InhibitorsAnti-emeticsAntibiotic AgentsAntibiotic DrugsAntibioticsAnticoagulant AgentsAnticoagulant DrugsAnticoagulantsAntidotesApoplexyArtificial IntelligenceAspirinBacteremiaBedsBleedingBlood VesselsBrain Vascular AccidentCardiacCardiac SurgeryCardiac Surgery proceduresCardiac infarctionCardiovascularCardiovascular Body SystemCardiovascular Organ SystemCardiovascular systemCaringCerebral StrokeCerebrovascular ApoplexyCerebrovascular StrokeCessation of lifeCharacteristicsClinicalCollaborationsComputer ReasoningCox Proportional Hazards ModelsCytochrome P-450Cytochrome P-450 Enzyme SystemCytochrome P450Cytochrome P450 Family GeneDataData BasesDatabasesDeathDecision MakingDeliriumDrug TargetingDrug TransportDrug usageDrugsEnvironmentEventExposure toFrequenciesFutureGenesGoalsHeart Surgical ProceduresHeart VascularHeart failureHemorrhageHeparinHeparinic AcidHomeHospitalsImmune responseImmunotherapeutic agentIndividualInformaticsInfrastructureInjury to KidneyInjury to LiverIntermediary MetabolismInterventionIntervention StudiesKininase II AntagonistsKininase II InhibitorsLabelLearningLengthLength of StayLifeLinear RegressionsLiver DysfunctionMachine IntelligenceMachine LearningMalignant HyperpyrexiaMalignant HyperthermiaMalignant hyperpyrexia due to anesthesiaMedicationMedicineMetabolic ProcessesMetabolismMethodologyMiscellaneous AntibioticMissionModelingMyocardial InfarctMyocardial InfarctionNSAIDsNaloxoneNarcanNarcantiNon-Steroidal Anti-Inflammatory AgentsNumber of Days in HospitalOperative ProceduresOperative Surgical ProceduresOpiatesOpioidOralOutcomeP450Patient CarePatient Care DeliveryPatientsPerioperativePersonsPharmaceutical PreparationsPharmacogenomicsPneumoniaPost-operative PainPostoperativePostoperative PainPostoperative PeriodPredicting RiskPrivate SectorProceduresReactionResearchResearch ResourcesResourcesRetrospective cohort studyRiskSafetySepsisSingle Base PolymorphismSingle Nucleotide PolymorphismStrokeSubgroupSurgicalSurgical InterventionsSurgical ProcedureTestingTheriacsTimeTreatment EffectivenessUpdateUrinary tract infectionUrinary tract infectious diseaseVariantVariationVenousVeteransVitamin KWarfarinWound Infectionanesthesia related hyperthermiaanti-emetic agentsanti-emetic drugsartificial neural netartificial neural networkbacteraemiabacterial bloodstream infectionbacterial infection in the bloodstreambeta blockerbeta-Adrenergic Blocking Agentsbeta-Adrenergic Receptor Blockadersblood lossblood thinnerbrain attackcardiac failurecardiac infarctcare for patientscare of patientscaring for patientscerebral vascular accidentcerebrovascular accidentcirculatory systemclassification treesclinical careclinical decision supportclinical practiceclopidogrelcomputational neural networkcoronary attackcoronary infarctcoronary infarctioncostcost effectivenessdata basedata warehousedeliriousdesigndesigningdrug metabolismdrug usedrug/agentforecasting riskfunctional statusheart attackheart infarctheart infarctionheart surgeryhepatic damagehepatic injuryhigh riskhomeshospital dayshospital length of stayhospital re-admissionhospital readmissionhospital stayhost responsehyperthermia of anesthesiaimmune drugsimmune system responseimmune-based therapeuticsimmunologic therapeuticsimmunoresponseimmunotherapeuticsimmunotherapy agentimprovedimproved outcomeinfected woundinnovateinnovationinnovativeintervention researchinterventional researchinterventional studyinterventions researchkidney dysfunctionkidney injuryliver damageliver injurymachine based learningmachine learning based methodmachine learning methodmachine learning methodologiesnew drug treatmentsnew drugsnew pharmacological therapeuticnew therapeuticsnew therapynext generation therapeuticsnon-steroidal anti-inflammatory drugsnovel drug treatmentsnovel drugsnovel pharmaco-therapeuticnovel pharmacological therapeuticnovel therapeuticsnovel therapyopiate exposureopioid exposurepain after surgerypain scorepatient centeredpatient orientedpatient subclasspatient subclusterpatient subgroupspatient subpopulationspatient subsetspatient subtypesperformance sitepharmacogenomic testingphenomicsphenotypic datapost-surgical painpostsurgical painpredict riskpredict riskspredicted riskpredicted riskspredicting riskspredictive riskpredicts riskprocess improvementprogramsprospectivere-admissionre-hospitalizationreadmissionregression treesrehospitalizationrenal dysfunctionrenal injuryresponse to therapyresponse to treatmentrisk predictionrisk predictionssingle nucleotide variantstrokedstrokessurgerysurgery outcomesurgery risksurgical outcomesurgical risksynthetic neural networktherapeutic responsetherapy responsethrombopoiesis inhibitorthrombotictreatment responsetreatment responsivenessurinary infectionvascular
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Description preview
Background: The VA Surgical Quality Improvement Program (VASQIP) predicts risk for important
postoperative outcomes and shares process improvements from high performance sites with lower
performance sites to continuously improve surgical outcomes. The VASQIP was so successful it was
implemented in the private sector and continues today. The…
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