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Precision Medicine Approach to Exercise-Based Interventions for Veterans with Knee Osteoarthritis

Organization DURHAM VA MEDICAL CENTERLocation DURHAM, UNITED STATESPosted 1 Sept 2023Deadline 28 Feb 2025 ⚠️
VANIHUS FederalResearch GrantFY2025Access to CareArthritisCaringCharacteristicsDataDegenerative ArthritisDegenerative polyarthritisDevelopmentEffectivenessEvidence based interventionExerciseFoundationsFundingGoalsHealth CareHealth Care SystemsHealth InstructionHealth Services AccessibilityHealth TutoringHealth educationHeterogeneityHomeHuman ResourcesIndividualInterventionKnee OsteoarthritisMachine LearningManpowerMeasurementMeasuresMethodologyMethodsMissionModelingNatureOsteoarthritisOsteoarthrosisOut-patientsOutpatientsPainPainfulParticipantPatientsPersonsPhysiatric ProcedurePhysiatricsPhysiatryPhysical MedicinePhysical Medicine ProcedurePhysical RehabilitationPhysical TherapeuticsPhysical therapyPhysiotherapyProcessQOCQOLQuality of CareQuality of lifeRandomized, Controlled TrialsRehabilitation MedicineReportingResearchResearch ResourcesResourcesRural HealthScienceSelf DirectionServicesSymptomsTestingTreatment outcomeTreesUnited States Department of Veterans AffairsUnited States Veterans AdministrationVeteransVeterans AdministrationVeterans AffairsVeterans Health AdministrationVeterans Health AffairsWOMACWestern Ontario and McMaster Universities Arthritis IndexWestern Ontario and McMaster Universities OsteoarthritisWorkaccess to health servicesaccess to servicesaccess to treatmentaccessibility to health servicesarmarthriticavailability of servicescare accessclinical relevanceclinically relevantcostcost effectivenessdegenerative joint diseasedesigndesigningdevelopmentaldisabilityeffectiveness testingexercise interventionexercise programexperiencefitness programhealth service accesshealth services availabilityhomeshypertrophic arthritisimprovedindexingindividual patientinnovateinnovationinnovativeknee OAknee joint OAknee joint osteoarthritismachine based learningmachine learned algorithmmachine learning algorithmmachine learning based algorithmmachine learning based modelmachine learning modelnovelopiate consumptionopiate drug useopiate intakeopiate useopioid consumptionopioid drug useopioid intakeopioid usepatient centeredpatient orientedpatient subclasspatient subclusterpatient subgroupspatient subpopulationspatient subsetspatient subtypespersonnelphysical activity interventionphysical rehabpragmatic effectiveness trialpragmatic trialprecision medicineprecision-based medicineprogramsrandomized control trialrandomized, clinical trialsrehabilitation serviceresponseservice availabilitystandard of caresupervised learningsupervised machine learningtreatment accesstreatment effecttreatment guidelinestreatment strategytrial comparing

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Description preview

Background: Knee osteoarthritis (OA) is a leading cause of pain and disability, and Veterans have markedly
greater rates than non-Veterans. Exercise is a core component of care for knee OA, associated with modest
average improvements in pain and function. However, there is tremendous variability in the degree of
improvement individual patients…

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