grant
Polyclonal Bi-Specific Vectored ImmunoTherapy to Functionally Cure HIV Infection
Organization MASSACHUSETTS GENERAL HOSPITALLocation BOSTON, UNITED STATESPosted 15 May 2024Deadline 31 Mar 2029
NIHUS FederalResearch GrantFY2025AIDS VirusAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAnimal ModelAnimal Models and Related StudiesAnti-Retroviral AgentsAntibodiesAssayBioassayBiological AssayCell BodyCellsCommunicable DiseasesDevelopmentDoctor of PhilosophyDoseDrugsEngineeringEscape MutantGene TransferGrantHIVHIV InfectionsHIV-1HIV-IHIV1HTLV-III InfectionsHTLV-III-LAV InfectionsHealthHuman Immunodeficiency Virus Type 1Human Immunodeficiency VirusesHuman T-Lymphotropic Virus Type III InfectionsHuman immunodeficiency virus 1Immune mediated therapyImmune responseImmune systemImmunologically Directed TherapyImmunotherapyIndividualInfectionInfectious DiseasesInfectious DisorderLAV-HTLV-IIILaboratoriesLymphadenopathy-Associated VirusMedicationMiceMice MammalsMissionMurineMusNHP modelsNIDANational Institute of Drug AbuseNational Institute on Drug AbuseNational Institutes of HealthOutcomePersonsPh.D.PhDPharmaceutical PreparationsPrincipal InvestigatorRegimenResearchSeriesSubstance Use DisorderTechnologyTestingTherapeutic InterventionUnited States National Institutes of HealthVirusVirus-HIVanti-retroviraldesigndesigningdevelopmentaldrug/agentengineered immune systemexperimentexperimental researchexperimental studyexperimentshost responseimmune engineeringimmune system responseimmune therapeutic approachimmune therapeutic interventionsimmune therapeutic regimensimmune therapeutic strategyimmune therapyimmune-based therapiesimmune-based treatmentsimmuno therapyimmunoengineeringimmunoresponseimprovedin vivointervention therapymedical collegemedical schoolsmodel of animalnew drug classnonhuman primate modelsnovelnovel drug classpolyclonal antibodyprofessorschool of medicinesubstance use and disordervector
Description preview
Project Summary / Abstract
This proposal describes the framework of a DP1 grant for Alejandro B. Balazs, PhD.
Dr. Balazs is currently an assistant professor at Harvard Medical School and a principal
investigator at the Ragon Institute of MGH, MIT & Harvard. Dr. Balazs' research is focused on
engineering the immune system via gene transfer as a…
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