grant
Pilot Study Characterizing Aerobic Exercise in Women with Systemic Lupus Erythematosus (Exercise SLE Pilot)
Organization CLINICAL CENTERLocation UNITED STATES
NIHUS FederalResearch GrantFY202521+ years oldAdultAdult HumanAerobic ActivityAerobic ExerciseAerobic TrainingAerobic fitnessAnaerobic ThresholdBlood flowCOVID crisisCOVID epidemicCOVID pandemicCOVID-19 crisisCOVID-19 epidemicCOVID-19 eraCOVID-19 global health crisisCOVID-19 global pandemicCOVID-19 health crisisCOVID-19 pandemicCOVID-19 periodCOVID-19 public health crisisCOVID-19 yearsCardiacCardiac ChronotropismCardiopulmonaryClinicClinicalDataData AnalysesData AnalysisData SystemsDiseaseDisorderEnrollmentEvaluableEvaluable DiseaseExerciseExercise TestFatigueGender BiasGoalsHeart RateIT SystemsImpairmentInformation SystemsInformation Technology SystemsLack of EnergyLupusLupus Erythematosus DisseminatusManuscriptsMeasurementMeasuresMediatingMedicineMitochondriaMotivationMuscleMuscle TissueNIAMSNational Institute of Arthritis, and Musculoskeletal, and Skin DiseasesNational Institutes of HealthO elementO2 elementOutcome MeasureOxygenPatient Outcomes AssessmentsPatient Reported MeasuresPatient Reported OutcomesPatientsPerceptionPerformancePhysical FunctionPhysical activityPilot ProjectsPreparationProtocolProtocols documentationPulmonary Gas ExchangeQuestionnairesRecommendationRegistriesReportingResearchResearch ActivityReview CommitteeSARS-CoV-2 epidemicSARS-CoV-2 global health crisisSARS-CoV-2 global pandemicSARS-CoV-2 pandemicSARS-coronavirus-2 epidemicSARS-coronavirus-2 pandemicSLEScienceSevere Acute Respiratory Syndrome CoV 2 epidemicSevere Acute Respiratory Syndrome CoV 2 pandemicSevere acute respiratory syndrome coronavirus 2 epidemicSevere acute respiratory syndrome coronavirus 2 pandemicSeveritiesSeverity of illnessSex BiasStable DiseaseSystemic Lupus ErythematosusSystemic Lupus ErythematousSystemic Lupus ErythmatosusTestingTimeUnited States National Institutes of HealthVisitWalkingWomanadulthoodcardiac functionclinical centercoronavirus disease 2019 crisiscoronavirus disease 2019 epidemiccoronavirus disease 2019 global health crisiscoronavirus disease 2019 global pandemiccoronavirus disease 2019 health crisiscoronavirus disease 2019 pandemiccoronavirus disease 2019 public health crisiscoronavirus disease crisiscoronavirus disease epidemiccoronavirus disease pandemiccoronavirus disease-19 global pandemiccoronavirus disease-19 pandemicdata interpretationdebilitating symptomdisease severitydisseminated lupus erythematosusenrollexercise programexercise trainingfitness programfunction of the heartheart functionimprovedlife spanlifespanmeasurable outcomemitochondrialmuscularoutcome measurementperipheral bloodpilot studypreparationsprimary outcomepulmonaryrecruitresponsesecondary outcomesedentarysevere acute respiratory syndrome coronavirus 2 global health crisissevere acute respiratory syndrome coronavirus 2 global pandemicsocialsystemic lupus erythematosistreadmilluptake
Description preview
Persistent, excessive fatigue is one of the most debilitating symptoms of SLE and is associated with functional limitations such as poor cardiorespiratory capacity and physical activity intolerance. Management of SLE-fatigue and the resultant physical debilitation has become a clinical and social challenge throughout the patients lifespan. Aerobic…
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