grant
Physiological determinants of suprathreshold deficits in sensorineural hearing loss
Organization UNIVERSITY OF PITTSBURGH AT PITTSBURGHLocation PITTSBURGH, UNITED STATESPosted 2 May 2025Deadline 30 Apr 2030
NIHUS FederalResearch GrantFY202621+ years oldAcousticsAdultAdult HumanAgeAnimal ModelAnimal Models and Related StudiesAnimalsAssayAttentionAudiogramAudiologyAudiometric TestAudiometryAuditoryBehaviorBehavioralBioassayBiological AssayBiological MarkersBrainBrain Nervous SystemBrain StemBrainstemCausalityCellular injuryClinicalCochleaCochlear OrganCodeCoding SystemCognitiveComplexCorti CellCuesDataDeafferentationDeafferentation procedureDevicesEEGEarplugElectroencephalogramElectroencephalographyEncephalonEnvironmentEquilibriumEtiologyExclusionExhibitsFrequenciesHair CellsHearingHearing AidsHearing LossHearing TestsHistoryHumanHypoacusesHypoacusisImpairmentIndividualIndividual DifferencesInjuryInstitutionInternal EarLabyrinthLoudnessMeasuresMechanicsMemoryModelingModern ManNatureNoiseOutcomeParticipantPatient RecruitmentsPatientsPerceptionPerformancePeripheralPhysiologicPhysiologicalPsychoacousticsPsychophysicsReaction TimeRecording of previous eventsRegistriesResearchResponse RTResponse TimeSensorineural DeafnessSensorineural Hearing LossSensorySensory Hearing LossSpeechSpeech PerceptionSpeech SoundTailTestingWorkadulthoodagesassistive hearing deviceassistive listening deviceauditory testsbalancebalance functionbasebasesbio-markersbiologic markerbiomarkercausationcell damagecell injurycellular damagecohortdamage to cellsdisease causationdysfunctional hearingear hair cellexperiencehearing amplificationhearing assessmenthearing assistancehearing assistive devicehearing challengedhearing defecthearing deficienthearing deficithearing devicehearing difficultyhearing dysfunctionhearing impairmenthearing in noisehearing loss therapyhearing loss treatmenthearing restorationhistorieshuman dataindexingindividual heterogeneityindividual variabilityindividual variationinjuriesinjury to cellsinner earinsightinterdisciplinary approachmechanicmechanicalmid lifemid-lifemiddle agemiddle agedmidlifemodel of animalmultidisciplinarymultidisciplinary approachneuralneural circuitneural circuitryneurocircuitrynoise perceptionparticipant recruitmentpersonalization of treatmentpersonalized medicinepersonalized therapypersonalized treatmentprogramspsychomotor reaction timepsychophysicalresponserestorationrestore hearingsensorineural hearing impairmentsoundsound frequencyspeech in background noisespeech in noisespeech in speech recognitionspeech recognition in noisestatisticssynaptic circuitsynaptic circuitrytreatment for hearing loss
Description preview
Current assessments and treatments for hearing loss focus on restoring hearing sensitivity and speech audibility through amplification. Yet, hearing-aid users struggle to understand audible speech, especially in environments with background noise. Little is known about the precise physiological mechanisms that contribute to the challenge of being…
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